Abstract

Integrated Microfluidic Devices For Enrichment and Detection of Circulating Biomarkers

Hyo-Il Jung, Professor, Yonsei University

The precise measurement or isolation of circulating biomarkers (CB) can serve as a powerful tool for cancer prognosis, diagnosis of minimal residual disease, assessment of tumor sensitivity to anticancer drugs, and personalization of anticancer therapy. The microfluidic device has a very strong advantage in comparison with   various modalities for the enrichment and separation of the CB in that it can be operated in a continuous manner minimizing any chance of loss. Over the past decade, our group has been working on various types of microfluidic-based enrichment and detection methods for the down-stream analysis of CBs. In this talk, I will present some of new discoveries and discuss critical concerns and future directions for the research.