Abstract

Molecular Point-of-Care SARS-CoV-2 Test using Solid State Nanopore Sensors

Andrea Chow, Senior Vice President of Engineering, Ontera Inc.

Ontera has developed a rapid point-of-care (POC) molecular test for detecting SARS-CoV-2 viruses based on nanopore sensors integrated into a microfluidic cartridge that contains all the reagents on board. The cartridge accepts an anterior nasal swab sample collected from an individual suspected of COVID-19. Upon inserting the cartridge into the instrument, the NanoDetector, all the operations included reagent addition, sample lysis, mixing, RTPCR, and detection are fully automated. We will present the test performance as well as the engineering challenges of designing the platform and how microfluidic technologies enable this POC applications with high sensitivity and fast time-to-answer.