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SELECTBIO Conferences Novel Formulation Strategies


Formulation of Water-Insoluble Drugs for IV Injections

Yogeshwar Bachhav, Associate Director Pharmaceutical Development, AiCuris Anti-infective Cures GmbH

The focus of the talk would be to cover critical attributes of the IV formulations such as pH, osmolality, drug load, absence of excipients with irritation potential, absence of precipitation upon mixing with plasma. It would also cover possible options to develop IV formulations of poorly soluble drugs or difficult to formulate drugs (one case study from the market or literature) viz.  Cyclodextrins (Captisol, HPBCD),  Liposomes,   Mixed micelles/miceller solutions (use of surfactants),  Intralipid emulsion, Nanosuspension. Some case studies would also be covered for difficulty  in formulating IV formulation is complex such as potent/cytotoxic drugs (case studies) e.g. anticancer drugs and Penicillin or cephalosporin type of compounds.

Add to Calendar ▼2018-04-12 00:00:002018-04-13 00:00:00Europe/LondonNovel Formulation StrategiesNovel Formulation Strategies in