Abstract

Patient-specific Functional Prediction of Cancer Drug Efficacy

Jens Kelm, CEO and Co-Founder, PreComb Therapeutics AG

In an effort to improve in vitro biology, tremendous progress has been made over the past decade in integrating cells into 3D dimensional configurations. While the various technologies for fabricating micro-physiology have improved significantly, the choice of the right cell type for each application remains. Cells as the building blocks for a 3D tissue model are an important determinant of its biological relevance. Here, I will present the current status to use patient-specific primary tumor cells as building blocks for 3D tumor models.