Abstract

Microphysiological Systems: Fluid Flow & Use of Multiple Organ Models on a Chip

Olivier Frey, Head of Technology and Platforms, InSphero AG

Microfluidic technology offers an important feature to 3D cultures and is the basis for Organ-on-Chip devices. We will review fluid flow enabling (a) a physiological environment including shear forces and pulsation, (b) nutrient supply and waste removal and (c) the interconnection of multiple organ models allowing studying organ-organ interaction and higher-order systemic model development.