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SELECTBIO Conferences Stem Cells in Drug Discovery Tox & Organoids 2019

Abstract



In vitro Safety Assays with Human-Derived Cardiomyocytes… Bridging the Translational Gaps?

Gary Gintant, Research Fellow, Abbvie

In vitro studies with human derived cardiomyocytes are increasingly being used for cardiovascular safety evaluations in candidate drug selection as well as regulatory assessments.  How well these models perform depend on level of recapitulation of the cardiac biology present in the experimental models as well as the questions being addressed and parameters being measured.  While the biology is critical, the successful use of these models to bridge the translational gaps between in vitro cardiomyocyte studies and clinical studies requires considering more than the cardiac biology.


Add to Calendar ▼2019-10-14 00:00:002019-10-15 00:00:00Europe/LondonStem Cells in Drug Discovery Tox and Organoids 2019Stem Cells in Drug Discovery Tox and Organoids 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com