Abstract

Efficacy and Safety of Fat Stem Cell Therapy in Breast Surgery

Lukas Prantl, Professor/Head, University of Regensburg

In the past years there has been an increasing demand for soft tissue augmentation for reconstructive and aesthetic purposes in medicine. In this respect adipose tissue has been of increasing interest, because of the relative ease of obtaining it from subcutaneous adipose tissue by liposuction and due to its comparably basic architecture and high plasticity making it suitable for universal soft tissue augmentation. Adipose-derived regenerative cells (ADRCs) contain several types of stem and regenerative cells, which help improve graft retention through multiple mechanisms. We have analyzed multiple confounding variables in harvesting, processing and grafting of lipoaspirate with regenerative cells to increase neovascularization and long-term graft survival. We will report our clinical experience involving 500 patients with fat transplantation.