Tuesday, 18 October 2016

08:30

Registration, Coffee and Pastries


Morning Session:
Session Chair: Lo Gorton, Professor, Lund University, Sweden

09:30

AC Electrokinetic Device for Isolation and Detection of Biomarkers and Other Disease Related Entities Directly from Blood
Stuart Ibsen, Research Associate, Moores Cancer Center, United Kingdom

The rapid isolation of cell free DNA, exosomes, viruses, and drug delivery nanoparticles directly from undiluted blood using a new alternating current electrokinetic microarray chip technology.

10:00

Darryl BornhopKeynote Presentation

Aptamer-Based Assays Combined with Backscattering Interferometry Enables Field-Setting Quantification of Nerve Agent Metabolites and Human Cytomegalovirus in Urine
Darryl Bornhop, Professor, Vanderbilt University, United States of America

Aptamer-probe based backscattering interferometric detection is fully quantitative in urine, with BSI-aptamer assays providing picomolar LOQ values for two metabolites of organophosphorus nerve agents and a few thousand molecules for structural proteins of human cytomegalovirus.

10:45

Coffee & Networking

11:15

Detection of Waterborne Viruses using Nano-Biomimetic Affinity Systems
Ibtisam Tothill, Professor, Cranfield University, United Kingdom

The talk will cover the synthesis of molecularly imprinted polymers (MIPs) nanoparticles as artificial receptor ligands against viruses and their use in an SPR based sensor to detect the target viruses.

11:45

Bio- and Biomimetic Sensors for Medical Diagnostics Based on the Heat-Transfer Method
Patrick Wagner, Professor, Soft-Matter Physics and Biophysics Section, Departement Natuurkunde en Sterrenkunde, Katholieke Universiteit Leuven, Belgium

The heat-transfer method HTM is a novel, label-free transducer principle, which allows detecting point mutations in DNA literally with just a heat-source and two thermometers. Other HTM applications include the detection of cancer cells, bacteria, neurotransmitters, and proteins.

12:15

Lunch & Networking

13:00

Poster Viewing Session


Afternoon Session:
Session Chair: Ibtisam Tothill, Professor, Cranfield University, United Kingdom

14:00

3rd Generation Biosensors for Sugar Analysis
Lo Gorton, Professor, Lund University, Sweden

14:30

Development and Challenges of Translating Viral Hemorrhagic Fever Research to Actionable Diagnostic Applications
Janice Duy, Researcher, ESRB-LASST, United States of America

Circulating microRNA populations are altered during Ebola virus infection. We have developed microRNA classifier of acute Ebola virus disease that predicted infection in presymptomatic primates. This model was deployed on human cases and correctly categorized infection status with high accuracy.

15:00

Coffee & Networking in Exhibition Hall

15:30

Printable Paper-Based Diagnostic Systems for Biomedical and Environmental Monitoring
John Brennan, Professor and Director, Biointerfaces Institute, McMaster University, Canada

The talk will focus on the development of printable components to produce bioactive paper sensors with a range of capabilities, including integrated sample preparation, biorecognition, amplification and readout technologies that can allow multi-step reactions on paper with ultra-sensitive detection capabilities.

16:00

Evolution of Monitoring for Giardia and Cryptosporidium in Water: 30 Years Research
Panagiotis Karanis, Professor and Director, Qinghai University, China

This overview discusses the different methods for detection of Cryptosporidium and Giardia in drinking and environmental waters. It includes a combination of conventional and molecular tools for the effective (oo)cyst recovery towards to the development of new concept for the diagnosis of waterborne protozoan.

16:30

Nanoparticle Based Analysis of Biomolecules, Cells and Tissue
Duncan Graham, Professor/Director, Strathclyde University, United Kingdom

Metal nanoparticles of silver or gold can be used to provide highly sensitive Raman scattering due to surface enhancement and can be exploited for the detection of biomolecules such as DNA or proteins and to image cells.

17:00

Networking Drinks Reception

18:00

End of Day 1

Wednesday, 19 October 2016


Morning Session:
Session Chair: Anthony Turner, Professor, Linkoping University, Sweden

09:00

Real-time Shape Approximation and 5-D Fingerprinting of Single Proteins
Michael Mayer, Professor, University of Fribourg, Switzerland

This talk describes the use of bilayer-coated, synthetic nanopores to characterize, simultaneously and in real-time, the volume, charge, shape, dipole moment, and rotational diffusion coefficient of single proteins.  This 5-D fingerprint may be used for sensitive biomarker detection and routine protein analysis.

09:30

Evaluation of a Resequencing Microarray Platform for Monitoring Genomic Drift in Ebola Virus
Robert Duncan, Principal Investigator, U S Food and Drug Administration, United States of America

10:00

Bo MattiassonKeynote Presentation

Combining Capacitive Biosensing with MIPs Offer a Competitive Alternative to Immunosensors
Bo Mattiasson, Professor, Lund University, Sweden

10:45

Coffee & Networking in Exhibition Hall

11:15

Phage-Derived Substitute Antibody Interface in Biosensors for Detection of Biological Threats
Valery Petrenko, Professor, Auburn University, United States of America

The talk summarizes the results of efforts in development of the landscape phage-based interfaces for analytical platforms, including threat-controlling biosensors, and their use for detection and monitoring of the panel of representative biological threats.

11:45

RNA Based Diagnosis of Antibiotic Resistance
Deborah Hung, Associate Professor, Broad Institute of MIT and Harvard, United States of America

Rapid diagnostics to rapidly identify a pathogen and provide drug susceptibility is critical for preparedness against bioterrorism. In particular, the need to generate real-time drug susceptibility patterns is mounting in the face of increasing natural antibiotic resistance and the possibility of engineered multi-drug resistant bioterrorist pathogens. The detection of RNA expression signatures can serve as such a diagnostic platform.

12:15

Lunch & Networking in Exhibition Hall

13:00

Poster Viewing Session


Afternoon Session:
Session Chair: Valery Petrenko, Professor, Auburn University, United States of America

14:30

Disposable Instruments for Biodetection
Anthony Turner, Professor, Linkoping University, Sweden

This presentation will describe the evolution of a new generation of printed sensing instruments, where not only the sensors are screen-printed, but also the circuits, displays and batteries. We are creating use-and-throw instruments for a wide range of sensing applications including the detection of multiple metabolites, microbial pathogens, drugs and toxins.

15:00

Coffee, Networking & Close of Conference