Registration

Welcome and Introduction to the Flow Chemistry Society
Ferenc Darvas, Chairman, Flow Chemistry Society, Switzerland

Production Applications of Flow Chemistry
David Ager, Principal Scientist, DSM Pharma Chemicals, United States of America

Flow methods can be used to control hazardous reactions and control by-product formation. This has been done at pilot and manufacturing scale.

Coffee Break and Networking in the Exhibition Hall

Applications of Flow to Advance Oncology Medicinal Chemistry Programs
Paul Richardson, Senior Principal Scientist, Pfizer Worldwide Research and Development, United States of America

This talk presents a focus on the application of flow chemistry within our current medicinal chemistry programs. In particular, emphasis is placed on examples where use of flow provides a significant advantage over the more conventional batch chemistry. 

Developments for Photochemistry in Flow
Aaron Beeler, Assistant Professor, Boston University, United States of America

Technology Spotlight:
Accelerating the Pace of Drug Development
Carl Beckett, General Manager, Covaris Process Technologies

Adaptive Focused Acoustics (AFA) is successfully being used for the processing of key nanoparticle delivery systems, including liposomes, emulsions and nanosuspensions.  AFA enables packaging of temperature and solvent sensitive APIs, while scaling from 100ul through continuous flow manufacturing processes.  

Lunch Break and Networking in Exhibition Hall

Poster Viewing Session

Streamlining Pharmaceutical Processes into Continuous Operations
Frank Gupton, Floyd D. Gottwald Chaired Professor, Virginia Commonwealth University, United States of America

The application of flow chemistry as a platform to improve chemical process operability will be presented with specific active pharmaceutical ingredient examples.  

Coffee Break and Networking in the Exhibition Hall

Dynamic Flow Enhanced Microfluidic Bioarray Reactions: Numerical Modeling and Experimental
Paul Li, Professor, Simon Fraser University, Canada

The dynamic flow in microfluidic channels has enhanced the chemical reactions in DNA hybridization. This study has assisted the design of an effective bioarray chip for the detection of fungal pathogen DNA (0.2 ng) and influenza antibody (5 attomoles). 

Close of Day One

Coffee Break and Networking in the Exhibition Hall

A High-Temperature/High-Backpressure Reactor for Performing Flowed Chemical Synthesis and In-Line, Real-Time Continuous Analysis and Process Optimization
Michael Organ, Professor, York University, Canada

A high temperature (e.g., 200 – 800 °C), high backpressures (e.g., >>1000 psi) flow reactor has been developed that uses microwave irradiation for obtaining high temperatures. The basic construction and operation of this system will be discussed including how samples are removed continuously without pressure loss and how samples are moved to analysis. 

Flow Chemistry: A Tool for New Developments from the Undergraduate Teaching Laboratory to the Fine Chemicals and Biofuels Industries
Nicholas Leadbeater, Associate Professor, University of Connecticut, United States of America

The presentation here will be split into two sections. Recent results from our research laboratory will be presented, focused around new organic chemistry in flow.  Attention will then be focused on development of flow chemistry experiments for use in the undergraduate teaching laboratory.

Catalysis in Flow: From Transition Metal Complex Synthesis to Synthesis with Catalysts
Tyler McQuade, Associate Professor, Florida State University, United States of America

Synthesis and use of catalysts in flow will be discussed. 

Lunch Break and Networking in Exhibition Hall

Poster Viewing Session

Microfluidic Electrochemical Synthesis: Investigating a New Tool for Oxidative Chemistry
Gregory Roth, Director/Associate Professor, Sanford Burnham Medical Research Institute, United States of America

Harnessing electrochemical synthesis at the laboratory bench has been a difficult and technology-limited task.  We describe a new continuous flow electrochemical reaction cell that is readily adapted to a commercial synthesis platform for performing redox chemistry.

Close of Conference