Thursday, 25 May 2017


Draft Agenda- Subject to Change

08:00

Registration

09:15

Welcome Address

09:25

Speakers Introduction & Memento Presentation


Session 1: Journey from Cancer Biomarkers Research to Commercial Products

09:45

Colvera™, A ctDNA Liquid Biopsy Assay for Colorectal Cancer. Our Journey from Discovery to the Clinic
Jason Ross, Sr Research Scientist And Team Leader, Commonwealth Scientific and Industrial Research Organisation, Australia

The speaker will discuss the journey that he and their collaborators undertook: from biomarker discovery and validation, to assay design and then to clinical trials and the launch of a commercial lab test.

10:25

Nanostring TechnologiesnCounter Analysis System: Moving from Genomic Discovery to Translational Research
Jay Manikandan, Field Application Scientist, Nanostring Technologies

10:55

Q/A Discussion

11:05

Beckman CoulterTechnology Spotlight:
Technological Advancements in Single Cell Analysis, helping in the Leukemia & Lymphoma Immunophenotyping and Circulating Tumor Cells Studies
Amitav Mohanty, Manager Market Development, Beckman Coulter

11:20

Coffee Break and Networking in Exhibition Area


Session 2: Circulating Cells & Nucleic Acids as Biomarkers for Cancer

11:50

Rajiv RajaKeynote Presentation

Cell-Free DNA (cfDNA) Analysis in Cancers: The New Frontier in Biomarker Analysis
Rajiv Raja, Director, MedImmune/ AstraZeneca, United States of America

In this talk, the current landscape of technologies used for cfDNA analysis in oncology will be presented. Results from the evaluation of changes in variant allele frequencies in response to therapy will be discussed.

12:30

MedGenome Labs Pvt LtdOncoTrackTM - Validation of NGS based Liquid Biopsy Assay for Monitoring Cancer Treatment
Vidya H Veldore, Principal Scientist , MedGenome Labs Pvt Ltd

This presentation will focus on validation of plasma circulating tumor DNA as biomarker for genomic testing in NSCLC patients: MedGenome in collaboration with India's Premeir Cancer Hospital. Key aspects of validation of a clinical diagnostic assay that includes concordance assessment between tissue biopsy and plasma CtDNA for biomarker status, specificity, sensitivity and diagnostic accuracy of the testing will be discussed.

13:00

Q/A Discussion

13:10

Lunch Break and Networking in Exhibition Area


Session 3: Technologies and Approaches for Targetting Cancer

13:50

“Moonlighting Functions” of Glycolytic Enzymes as Emerging Targets for Preventing Cancer Cell Invasion and Metastasis
Hirak Basu, Associate Professor, University of Texas MD Anderson Cancer Center, United States of America

This talk will focus on novel therapeutic agents that target oxidative modifications in prostate cancer cells .It will also discuss how these agents are currently undergoing preclinical development for clinical trials.

14:30

Identifying Potential Therapeutic Targets in Gallbladder Cancer using Proteomic Strategies
Tejaswini Subbannayya, Research Scientist, Institute of Bioinformatics, India

This talk will highlight the potential therapeutic targets to improve Gallbladder cancer (GBC) treatment options and disease outcome. To this end, it will also discuss various proteomic strategies that were employed to study the pathobiology in GBC using GBC cell lines.

15:10

Q/A Discussion

15:20

Coffee Break and Networking in Exhibition Area


Session 4: Technologies and Approaches for Targeting Cancer- II

15:35

Ashish GautamKeynote Presentation

New Frontiers in Targeted Therapy: ADCETRIS® (Brentuximab vedotin) a CD30 directed Antibody Drug Conjugate
Ashish Gautam, Global Brand Medical Head - ADCETRIS, Takeda Oncology, United States of America

The presentation will cover topics related to Development, Mechanism Pathway, Published Data from Studies & Ongoing Clinical Development Studies of ADCETRIS® (brentuximab vedotin).

16:35

Integrating Peptide Drug Conjugates with Radiotherapy
Sunil J Advani, Associate Professor & Associate Division Director Clinical and Translational Research, University of California, San Diego, United States of America


Session 8: Academic Research in Oncology

17:15

Q/A Discussion

17:25

Open Discussion Session: Cancer Diagnosis and Treatment - The Oncologist’s Viewpoint
Experts: Vinayak V Maka, Associate Professor, Medical Oncology, Ramaiah Medical College and Hospitals, India Rohit; Raghunath Ranade, Consultant Gynecological Oncologist and Robotic Surgeon, Narayana Health Mazumdar Shaw Cancer Centre, India; Nanda Rajaneesh, Surgical Oncologist, Apollo Spectra Hospitals, India; K R Madhava, Medical Oncologist BGS Global Hospitals, India

18:00

Coffee & End of First Day of Conference

Friday, 26 May 2017

09:00

Draft Agenda- Subject to Change


Session 5: Cancer Immunotherapy

10:00

Swapna ChaudhuriKeynote Presentation

The Multi-Potent Novel Biomolecule T11 Target Structure (T11TS) helps in Malignant Glioma Abrogation: A Preclinical Study
Swapna Chaudhuri, Professor, Calcutta School of Tropical Medicine, India

The Presenter will discuss their work on Glioblastoma and will show how Immunotherapy with T11TS (a glycopeptide derived from SRBC) on an established rat model of glioma rejuvenates the deserted immune system and causes profound immune potentiation both at the peripheral and intracranial levels. It will also discuss how T11TS, when administered in three doses to glioma-bearing rats, helps in glioma abrogation by reversing the glioma-induced changes in the T-cell signaling pathway and by steering the pathway in the positive direction. To unearth the root of this immune suppression due to glioma, the modulation of hematopoietic stem cells and their apoptotic death were also studied which will be covered during the talk. Modulation of HSCc during glioma and treatment with T11TS therapy indicates the regenerative power of T11TS.Taken together, the talk will highlight their findings which suggest that T11TS can be introduced as an effective anti- neoplastic agent.

11:00

Q/A Discussion

11:05

Coffee Break and Networking in Exhibition Area


Session 6: Current Approaches in Cancer Therapeutics

11:35

NRF2-mediated changes in Glutathione Metabolism mediate the resistance of EGFR-T790M Mutant Lung Cancer Cells to Erlotinib
Olivier Pardo, Team Leader, Imperial College London, United Kingdom

The speaker will discuss about Metabonomics profiling of erlotinib-sensitive/resistant cells along with how, by using RNA interference and pharmacological inhibitors of GSH pathway enzymes, increasing GSH levels in ER cells sensitises these to erlotinib. Conversely, reducing GSH levels renders sensitive cells resistant to the drug. It will finally highlight how their data identifies a new resistance mechanism to EGFR TKIs and propose a novel therapeutic strategy to tackle this problem in the clinic.

12:15

Delineating Tobacco induced Cellular Transformations in Oral Cancer
Aditi Chatterjee, Faculty Scientist, Institute of Bioinformatics, India

This talk will discuss how both chewing and smoking tobacco causes oral cancer but the molecular alterations brought about by each insult is different. Amongst the proteins which was overexpressed in both smoked and smokeless form of tobacco was Stearoyl-CoA desaturase. The presenter will highlight that SCD can act as a potential therapeutic target in head and neck squamous cell carcinoma, especially in patients who are users of tobacco.

12:55

SBPL-0600: An Oncolytic Virotherapy with a Potential to Personalize Cancer Therapy
Vishwas Joshi, Director, Seagull BioSolutions Pvt Ltd, India

13:25

Signaling Mechanisms in Brain Tumor Initiating Cells
Neha Garg, Assistant Professor, IIT Mandi, India

13:55

Q/A Discussion

14:05

Lunch Break and Networking in Exhibition Area


Session 7: Advances in Biofluid-based Biopsies

14:50

Impact of Circulating Tumor Cells Heterogeneity for Monitoring Cancer Immunotherapy Effectiveness and Clinical Outcomes
Shibichakravarthy Kannan, Founder & CEO, Theranosis Life Sciences Pvt Ltd, India

15:20

Non Invasive Assessment of IL6 Levels in Patients with Oral Cancer
Susanna T, Assistant Professor, Sri Devaraj Urs Medical College, India


Session 8: Academic Research in Oncology

15:50

Q/A Discussion

16:00

Coffee Break and Networking in Exhibition Area

16:15

Case Study: Piramal Development Approach to an Early Phase ADC
Maria Kowal, Protein Scientist, Piramal Pharma Solutions, United Kingdom

16:35

Q/A Discussion

16:40

T11TS repress Glioma Mediated Apoptosis in Hematopoietic Stem Cells by Controlling both Extrinsic and Intrinsic Cascade of Cell Death and also rescue from Granzyme B Regulated Gliomagenic Killing
Somnath Mondal, PhD Fellow, Calcutta School of Tropical Medicine, Kolkata, India

16:50

Design of Novel Antagonists of Matrilysin through Advanced Pharmacophore based Virtual Screening and Molecular Dynamics Simulations
Sudheer Kumar Katari, Research Scholar, Sri Venkateswara Institute of Medical Sciences University, India

17:00

Complete Assignments of Extraction, Isolation and Characterization of Prostate Cancer Chemopreventive Compound Taraxerol from Bark Annona reticulata L. on Human Prostate Cancer Cell Line (LNCaP and PC-3 cell lines)
Saritha Surapaneni, Research Scholar, Acharya Bm Reddy College of Pharmacy, India

17:10

Signal Transduction Inhibitors from C. rotundus
Lydia Charles, Student, Bharathiar University, India

17:20

Q/A Discussion

17:30

Closing Remarks and Vote of Thanks

17:35

End of Conference