Thursday, 22 January 2015


Agenda

08:00

Registration

09:00

Inauguration


Session 1: Flow Chemistry for Industrial Scale & API Synthesis / Session Chair: Dr. P V Srinivas

09:30

C. Oliver KappeKeynote Presentation

The Use of Continuous Flow Technology Towards the Synthesis of APIs
C. Oliver Kappe, Professor and Scientific Director, Center for Continuous Flow Synthesis and Processing, University of Graz, Austria

This presentation will highlight studies in the field of continuous flow processing. Emphasis will be given to highly atom efficient and process intensified chemical transformations useful for the synthesis of APIs or key intermediates that are often too hazardous to be executed in a batch reactor.

10:10

Q/A Session

10:15

Continuous Flow Synthesis: Laboratory Approach & Protocol for Scale-up
Amol Kulkarni, Scientist, National Chemical Laboratory, India

10:50

Q/A Session

10:55

From Batch to Continuous Flow Processing: Development of Safe and Improved Methods for Aerobic Oxidation
Alain Favre-Reguillon, Associate Professor, University of Lyon, France

This talk will highlight the advantages of continuous flow gas-liquid processes for aerobic oxidation of aldehydes and alcohols. The simple experimental setup in combination with the benefits given by continuous flow technology, including safety, renders the procedure synthetically very interesting and we will show that high throughput screening of experimental conditions resulted in the development of improved protocols.

11:30

Q/A Session

11:35

Coffee Break and Networking in Exhibition Area


Session 2: Micro & Continuous Flow Reactors and Systems / Session Chair: Dr. Luigi La Vecchia

12:05

Paul WattsKeynote Presentation

From Micro Reactor Research to Meso Reactor Synthesis and Production
Paul Watts, Distinguished Professor and Research Chair, Nelson Mandela University, South Africa

12:45

Q/A Session

12:50

Flow Chemistry Today: Towards Multistep (Enzymatic) Processes
Floris Rutjes, Professor, Radboud University Nijmegen, Netherlands

The talk will focus on the integration of additional unit operations in a single flow system,including extraction (workup) and subsequent reaction steps to create multistep processes. Several examples will be discussed, such as enzymatic cascades, or reactions in which enzymes are combined with conventional reaction steps.

13:25

Q/A Session

13:30

Syrris Scientific Equipment Pvt LtdTechnology Spotlight:
Flow Chemistry Tool Kit – Novel Technology and Chemistry including Electrochemistry in Flow
Subramaniam Raman, Regional Director, Syrris Scientific Equipment Pvt Ltd

13:45

Lunch Break and Networking in Exhibition Area


Session 3: Flow Reactor Scale up - Issues & Solutions / Session Chair: Dr. Ravi Sobti

14:35

Scalability of Multiphase Transport Processes using Advanced Flow Reactors
Simon Kuhn, Associate Professor, Katholieke Universiteit Leuven, Belgium

This talk will present a detailed experimental heat and mass transfer study of micro- and milli-scale reactors to predict the scalability of heat and mass transfer coefficients across several orders of length scale. Furthermore, a modelling strategy based on computational fluid dynamics (CFD) will be presentated which enables further design improvements of advanced flow reactors.

15:10

Q/A Session

15:15

Application of Continuous Flow Chemistry in a Pharmaceutical Environment
Luigi La Vecchia, Director, Novartis Institutes for BioMedical Research, Switzerland

The presentation will describe the application of Continuous Flow Chemistry for scaling-up exothermic or hazardous reactions.

15:50

Q/A Session

15:55

Scalable Flow Chemistry: A Flexible Tool for the Research, Development and Production of Pharmaceuticals, Fine & Specialty Chemicals
Charlotte Wiles, Chief Executive Officer, Chemtrix BV, Netherlands

16:30

Q/A Session

16:35

Industrial Flow Chemistry - TOOL BOX (Successful Reactions)
Vijay Kirpalani, CEO, Pi-Process Intensification Experts LLP, India

17:10

Q/A Session

17:15

Coffee Break and Networking in Exhibition Area

17:30

End of First Day of Conference

Friday, 23 January 2015


Session 4: Process Intensification using Flow Reactors / Session Chair: Dr. Sanjay Gade

09:30

Process Intensification Utilizing High-Temperature/Pressure Flow Chemistry
C. Oliver Kappe, Professor and Scientific Director, Center for Continuous Flow Synthesis and Processing, University of Graz, Austria

In this talk, the execution of a number of synthetically valuable organic transformations in a high-temperature/high-pressure continuous flow format will be described, including monophasic and multiphasic (liquid/liquid, gas/liquid) processing conditions. This presentation will also focus on Chemistry examples which includes the formation of heterocycles, transition metal-catalyzed C-C couplings, and several reduction and oxidation processes that can safely be conducted in a continuous flow environment.

10:05

Q/A Session

10:10

Process Intensification: Cavitational Flow Reactors
Avvaru Balasubrahmanyam , Sr. Manager , Reliance Industries Ltd, India

10:45

Q/A Session

10:50

Corning Technologies India Pvt LtdTechnology Spotlight:
Corning Advanced Flow Reactor Technology - Industrial Production Made Real
Praveen Gosain, Regional Director, Corning Technologies India Pvt Ltd

11:05

Coffee Break and Networking in Exhibition Area


Session 5: Biocatalysis/Catalysis in Flow / Session Chair: Dr. A V Karnik

11:35

Efficient & Viable Bio-Catalysis in Flow
Madhav Sapre, Chief Technology Officer, Pi-Process Intensification Experts LLP, India

12:10

Q/A Session

12:15

Rate-based Experimental Design using Continuous Flow Reactors
Christopher Hone, Research Scholar, University of Leeds, United Kingdom

A novel methodology which implements experimental design campaigns for the generation of process rate models based on fitting a simplified kinetic motif will be presented. The rate models are then used for the optimisation and scale-up of continuous flow processes.

12:50

Q/A Session

12:55

Zaiput Flow TechnologiesTechnology Spotlight:
Integrated Liquid-Liquid Separator and its Uses in Flow Chemistry
Andrea Adamo, Chief Executive Officer, Zaiput Flow Technologies

13:10

Poster Evaluation

13:40

Lunch Break and Networking in Exhibition Area


Session 6: Novel Applications of Flow Chemistry / Session Chair: Dr. Oliver Kappe

14:40

Handling Slower Reactions in Flow
Robert Ashe, Managing Director, AM Technology, United Kingdom

15:15

Q/A Session

15:20

Novel Applications of Flow Chemistry in Industry and Academia
Andrew Mansfield, Application Specialist, Vapourtec Ltd, United Kingdom

15:55

Q/A Session

16:00

Photocontrolled Polymerizations in Flow: Next Generation Material Synthesis
Thomas Junkers, Professor, Hasselt University, Belgium

In this presentation the use of various UV sources in the copper-redox initiated controlled polymerization of (meth)acrylates will be highlighted and the efficiency of these reactions discussed with respect to the overall quality of materials that can be obtained in this pathway, ranging from multiblock copolymers to star-shaped polymeric drug carriers.

16:35

Q/A Session

16:40

Award Presentation & Vote of Thanks

16:50

Coffee Break and Networking in Exhibition Area

17:10

End of the Conference