08:00 |  Free Workshop
PCR without DNA purification – Thermo Scientific Direct PCR
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Session: Lab-on-a-Chip Applications: Point of Care |
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09:00 |  | Keynote Presentation A System for Continuous Monitoring of Subcutaneous Glucose Based on Microfluidics and Microdialysis
Elisabeth Verpoorte, Chair of Analytical Chemistry and Pharmaceutical Analysis, University of Groningen, Netherlands
The surge in new diabetes patients caused by Western-style diet and a sedentary lifestyle continues to drive the development of glucose sensing technologies and portable monitoring systems. In this presentation, we consider the use of microfluidics coupled with microdialysis as the basis of a miniaturized system for continuous monitoring of glucose in subcutaneous tissue. |
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09:30 | Multifunctional Nanoparticles for an Integrated Microfluidic Diagnosis System
Sofia Dembski, Researcher, Fraunhofer Institute for Silicate Research, Germany
The great potential of nanoparticles in early diagnosis was recently demonstrated by a joint research project aiming to create a portable microfluidic diagnostic device capable of simultaneously detecting relevant biomarkers such as e.g. tumor-specific or cardiological markers with detection sensitivity even below 10-11 mol/l. |
10:00 | A Multiplexed Localized Surface Plasmon Based Biosensor Based on Gold Nanorings for Point of Care Applications
Liesbet Lagae, Group Leader, IMEC, Belgium
A compact lab on chip system, cheap and easily parallelizable, was developed based on the localized surface plasmon resonance (LSPR) properties of gold nanoring covered substrates integrated with a multichannel microfluidic disposable and a compact CCD read out. The device was applied to simultaneously monitor the biomolecular interactions with label free and in real-time for both proteins and DNA. The investigation of the kinetic biomolecular interactions give a good indication how assay times could be further reduced of particular importance for point-of-care diagnostic applications. Furthermore, we will show the potential of these gold nanostructures for advanced LSPR sensing and Surface Enhanced Raman Scattering (SERS) spectroscopy. |
10:30 | Coffee and Networking in Main Exhibition Hall |
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Session: Cell and Particle Handling, Sample Preparation and Separation |
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11:15 | Rapid Clinical Diagnostics in a Continuous Flow Lab-on-a-Chip
Nicole Pamme, Professor in Analytical Chemistry, Stockholm University, Sweden
We present a fast, highly versatile microfluidic platform which utilises mobile magnetic particles for performing surface-based assays in continuous flow within a fraction of the time required for conventional methods. |
11:45 | Recent Advances in Separating, Counting and Identification of Bioparticles in Centrifugal Lab-on-a-Chip Systems
Jens Ducrée, Doctor, Dublin City University, Ireland
This presentation highlights recent advances of high-efficiency particle capture, retention, counting, identification and aliquoting by making specific use of the centrifugal volume force, scale-matched geometrical features and integrated actuation. These lab-on-a-disc technologies leverage new applications such as the definition and counting of total particle numbers as well as multiplexed screening in bead and cell based assays implemented on low-complexity instrumentation. |
12:15 | Lunch and Networking in Main Exhibition Hall |
12:45 |  Free Workshop
Glosensor Technology: Intracellular Biosensors to Detect Signal Transduction in Living Cells
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13:15 | Poster Presentations |
13:30 |  Free Workshop
Automatic High Content Screening for Life Sciences
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14:15 | Applications of Microchip Acoustophoresis
Thomas Laurell, Professor, Lund University, Sweden
Acoustophoresis allows non-perturbing manipulation and separation of cells in microfluidic systems. This opens the route to rapid processing of crude biological samples for medical diagnostics as well as other biofluids. The recent advancements of acoustophoresis and applications within life science will be overviewed. |
15:15 | Coffee and Networking in Main Exhibition Hall |
16:00 | Two-Dimensional Protein Separation in Microfluidic Devices
Z Fan, Professor, University of Florida, United States of America
Two-dimensional protein electrophoresis has been implemented in plastic microfluidic devices. An array of microvalves was integrated for introducing different separation media. The total separation time was much shorter than the conventional approach. |
16:30 | Polymeric Micro-Fabricated TiO2-ZrO2 Affinity Chromatography Microchip for Phosphopeptide Enrichment and Separation
Katerina Tsougeni, NCSR Demokritos, NCSR Demokritos, Greece
We demonstrated a completely microfabricated affinity microcolumn on a polymeric chip design for the effective enrichment and separation of phosphopeptides using off-chip MALDI MS identification. The microcolumn exhibited large chromatographic capacity and can be used several times with reproducible results. |
17:00 | Close of Conference |
