| Conferences \ Indian Lab Automation \ Advances in Genomics, Informatics and Bioanalysis \ Agenda \ Jogeswar Purohit |
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Characterization of a Novel Moonlighting Histone H3 Specific Protease Activity by a Known NAD+ Dependent Dehydrogenase From Chicken LiverTuesday, 30 October 2012 at 16:00  Add to Calendar ▼2012-10-30 16:00:002012-10-30 17:00:00Europe/LondonCharacterization of a Novel Moonlighting Histone H3 Specific Protease Activity by a Known NAD+ Dependent Dehydrogenase From Chicken LiverSELECTBIOenquiries@selectbiosciences.comSite-specific proteolysis of the N or C-terminus of histone tails has recently emerged as a novel form of irreversible post-translational modifications assigned to histones. In the present study liver specific proteolysis of histone H3 in adult chicken liver tissue is demonstrated. The proteolysis removes 23 amino acids from the N-terminus of histone H3. We further demonstrate a histone H3 specific protease (H3ase) activity in the chicken liver nuclear extract. H3ase was purified to homogeneity |
Add to Calendar ▼2012-10-30 00:00:002012-10-31 00:00:00Europe/LondonAdvances in Genomics, Informatics and BioanalysisSELECTBIOenquiries@selectbiosciences.com
