R Kannan's Biography

R Kannan, Scientist Fellow, CSIR-CFTRI

Dr. Kannan Rangiah is currently working as a Scientist Fellow at Central Food Technological
Research Institute (CSIR-CFTRI), Mysore. Before that, he worked as a Facility In-Charge for Metabolomics facility at Centre for Cellular and Molecular Platform (C-CAMP), NCBS Campus,
Bangalore, India. He has done his Ph.D in International Center for Genetic Engineering and
Biotechnology (ICGEB), New Delhi (2005). During his research work he had proposed a new mechanism of action of the antimalarial drug Artemisinin and also developed a screening method to look for antimalarials from natural sources. He joined pharmacology department to do his postdoctoral training (from 2006 to 2011) at Center for Cancer Pharmacology, University of Pennsylvania (UPENN), Philadelphia and worked under Prof. Ian A. Blair at UPENN. He has worked on colon cancer proteomics, quantification of nicotine metabolites from smoker’s urine sample, quantification of estrogens from postmenopausal woman sera. He has been exposed to different kinds of mass spectrometry instruments (ion-trap, orbi-trap and triple quad) to do both
qualitative and quantitative experiments from various biological fluids. He has joined C-CAMP on
July 2011 and he had setup an excellent UHPLC-MS based metabolomics facility to do both targeted
and untargeted metabolomics from various biological fluids. He has developed different UHPLCMS/SRM methods to quantify amines, phenolics, neem metabolites and Olanzapine drug metabolites. He has also developed a workflow to do comparative metabolomics in smoker/nonsmoker urine sample by using HRMS system. His current interest is in developing methods to quantify at least 1000 metabolites from biological fluids as a readout of phenotype and also called as “metabotype”. He has also developed various quantification methods for the absolute quantification of bio-molecules using Stable Isotope Dilution (SID) methodology.