Approaches For Validation of Liquid Biopsy Testing of Circulating Tumour DNAThursday, 25 October 2018 at 16:00 Add to Calendar ▼2018-10-25 16:00:002018-10-25 17:00:00Europe/LondonApproaches For Validation of Liquid Biopsy Testing of Circulating Tumour DNAExosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com The typically low concentration of ctDNA in cancer patients’ samples makes validation of analytical sensitivity a critical element in the assessment of a diagnostic test. The potential for real-time monitoring of tumor dynamics through liquid biopsy testing also necessitates a systematic evaluation of quantitative accuracy. This presentation will discuss approaches to validate the performance of targeted methods for cancer mutations, including pre-analytical controls, and the development of reference materials and reference measurement procedures, which also support longer-term comparability and standardization of patient testing. |