Targeting Protein-Protein Interactions in Oncology with Fragment Based Drug DiscoveryWednesday, 23 March 2016 at 09:00 Add to Calendar ▼2016-03-23 09:00:002016-03-23 10:00:00Europe/LondonTargeting Protein-Protein Interactions in Oncology with Fragment Based Drug DiscoveryAcademic Drug Discovery 2016 in Cambridge, UKCambridge, UKSELECTBIOenquiries@selectbiosciences.com In the Drug Discovery Programme at the Cancer Research UK Beatson Institute we are exploiting the basic biology strengths within the Institute and wider Cancer Research UK network, to investigate some of the most exciting and challenging cancer targets. This includes targeting mechanisms important in invasion and metastasis as well as highly validated but challenging protein-protein interaction (PPI) targets. I will describe our forays in this area which involve fragment based methods of hit identification coupled with structure based compound evolution. |