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SELECTBIO Conferences BioMEMS, Microfluidics & Biofabrication: Technologies and Applications

Rong Fan's Biography

Rong Fan, Associate Professor of Biomedical Engineering; Director, Single-Cell Profiling Core, Yale University

Rong Fan is Associate Professor of Biomedical Engineering at Yale University. He received a Ph.D. in Chemistry from the University of California at Berkeley followed by a postdoctoral training at Caltech in the field of cancer nanotechnology. His research interest at Yale University is centered on the development of an array of single-cell omics technologies to analyze deep functional heterogeneity in human cancers and the immune system. He is directing the Single-Cell Profiling Core of the Dana Farber Physical Sciences Oncology Center (PS-OC) program. He is the recipient of numerous awards including the Howard Temin Pathway to Independence award from National Cancer Institute, the NSF Early Stage Faculty Career Development (CAREER) Award, and the Packard Fellowship for Science and Engineering.

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Single-Cell Functional Proteomics: Small Devices for Big Impact

Thursday, 16 March 2017 at 14:30

Add to Calendar ▼2017-03-16 14:30:002017-03-16 15:30:00Europe/LondonSingle-Cell Functional Proteomics: Small Devices for Big

Dr. Fan will discuss novel technologies for single-cell proteomic profiling, in particular, a microchip technology for co-detection of 40+ functional proteins such as cytokines/chemokines at the level of single cells, representing the highest multiplexing recorded to date for a single-cell protein secretion function assay. This technology permits the full-spectrum dissection of anti-tumor T cell functions, correlating to clinical outcomes and potentially predicting therapeutic efficacy and toxicity.  Applying this technology to leukemic cells from patients identified the existence of polyfunctional cell populations associated with pathogenesis and therapeutic response. All these underscore the importance of measuring functional proteomic heterogeneity even in phenotypically identical cell populations in order to evaluate the quality of cell-based therapeutics or to monitor patient responses for precision medicine.

Add to Calendar ▼2017-03-16 00:00:002017-03-17 00:00:00Europe/LondonBioMEMS, Microfluidics and Biofabrication: Technologies and