| Conferences \ Circulating Biomarkers World Congress 2015 \ Circulating DNA, Circulating RNA, Circulating Tumor Cells \ Agenda \ Saumya Das |
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A Functional Role for Extracellular RNAs as Biomarkers in Cardiovascular DiseasesMonday, 23 March 2015 at 17:30  Add to Calendar ▼2015-03-23 00:00:002015-03-23 01:00:00Europe/LondonA Functional Role for Extracellular RNAs Biomarkers in Cardiovascular DiseasesSELECTBIOenquiries@selectbiosciences.comAs the treatment for acute coronary syndromes has improved in the last decade, the sequelae of myocardial infarction such as heart failure and ventricular arrhythmias have increasingly contributed to morbidity, mortality and health care expenditure. Novel strategies to understand ventricular remodeling after myocardial infarction and onset of heart failure are critical to development of novel biomarkers to identify vulnerable patients and novel pathways for therapeutic intervention. Biomarkers that are functionally implicated in disease pathogenesis may be particularly robust and shed light on novel disease specific pathways. This presentation focuses on novel extracellular RNA biomarkers present in different plasma compartments and discusses their role as diagnostic and prognostic biomarkers. The specific case of microRNA-30d as a prognostic biomarker for cardiac remodeling and its functional role in remodeling is discussed in detail. The application and challenges of next generation sequencing to discover novel extracellular RNA biomarkers are addressed. |
Add to Calendar ▼2015-03-23 00:00:002015-03-24 00:00:00Europe/LondonCirculating DNA, Circulating RNA, Circulating Tumor CellsSELECTBIOenquiries@selectbiosciences.com
