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SELECTBIO Conferences The Space Summit 2019

Mary Kearns-Jonker's Biography



Mary Kearns-Jonker, Associate Professor, Loma Linda University School of Medicine

Dr. Kearns-Jonker is as an Associate Professor in the Department of Pathology and Human Anatomy at Loma Linda University School of Medicine where she is Co-Director of the Cancer, Developmental and Regenerative Biology Program. She completed her graduate training at McGill University in Montreal, Quebec and her postdoctoral training at the National Institutes of Health. As an Assistant Professor in the Department of Cardiothoracic Surgery at the University of Southern California Keck School of Medicine, she utilized her training to focus on developing alternative solutions for patients with end-stage organ failure, including xenotransplantation and stem cell transplantation. After accepting a position at Loma Linda University, she expanded the scope of her team’s research to include studies focused on neonatal cardiovascular stem cells and their potential for cardiovascular repair in vivo and utilization of the International Space Station as a platform to study the impact of microgravity on human cardiovascular progenitors.

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Human Cardiovascular Progenitor Cell Culture on the International Space Station

Monday, 14 October 2019 at 11:15

Add to Calendar ▼2019-10-14 11:15:002019-10-14 12:15:00Europe/LondonHuman Cardiovascular Progenitor Cell Culture on the International Space StationThe Space Summit 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Microgravity and the spaceflight environment influences the transcriptome, function and differentiation of cardiovascular progenitor cells.  Our research team studied the effect of spaceflight on human cardiovascular progenitor cells which were flown aboard the International Space Station for 30 days and recovered live to Earth.  Spaceflight and the microgravity environment was found to impact mechanotransduction, cardiogenesis, cell cycling, DNA repair, and signaling events.  Microgravity exposure was associated with enhanced proliferative potential and migration as well as elevated expression of paracrine factors.  Neonatal human cardiovascular progenitor cells cultured in space demonstrated enhanced stemness.  This presentation will discuss our findings and the relevance of these results for stem cell based applications on Earth and cardiovascular progenitor cell function in space.


Add to Calendar ▼2019-10-14 00:00:002019-10-15 00:00:00Europe/LondonThe Space Summit 2019The Space Summit 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com