
Conferences \ RNA-Seq, Single Cell Analysis & Single Molecule Analysis 2017 \ Agenda \ Eric Clambey |
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Characterizing Virus Infection Heterogeneity by Simultaneous Measurement of RNA Expression and DegradationThursday, 5 October 2017 at 13:00 ![]() Virus-host interactions studied in bulk populations obscure cell-to-cell variation. Here we quantify RNA expression and degradation at the single-cell level during virus infection, combining a sensitive and robust fluorescent in situ hybridization platform with multiparameter flow cytometry and high throughput cell imaging. This strategy reveals heterogeneity of gene expression during virus infection in both prominent and rare cell populations. |