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Genome-Wide Screen Reveals Cellular Factors Required for Coronavirus Replication

Tuesday, 12 November 2013 at 10:45

Add to Calendar ▼2013-11-12 10:45:002013-11-12 11:45:00Europe/LondonGenome-Wide Screen Reveals Cellular Factors Required for Coronavirus Replication Screening Asia in SingaporeSingaporeSELECTBIOenquiries@selectbiosciences.com

Coronaviruses are RNA viruses with a large zoonotic reservoir and propensity for host switching, representing a real threat for public health, as evidenced by SARS and the emerging MERS. Cellular factors required for their replication are poorly understood. Using genome-wide siRNA screening, we identified 83 novel genes supporting infectious bronchitis virus (IBV) replication in human cells.