E Antonio Chiocca's Biography

E Antonio Chiocca, Professor and Chairman, Department of Neurosurgery, Brigham and Women's Hospital/Harvard Medical School

Dr. Chiocca is the Harvey Cushing Professor of Neurosurgery at Harvard Medical School and is the Chairman Neurosurgery at the Brigham and Women’s Hospital. He was previously Chairman of the Department of Neurosurgery at the Ohio State University Medical Center. He has been continuously funded by the NIH since 1996. He has more than 300 peer-reviewed publications, some in journals such as Nature Medicine, Nature Biotechnology, Molecular Cell, and PNAS. He has elucidated how viruses with specific gene mutations will replicate selectively in tumors with a specific defect in a tumor suppressor pathway. He has also shown how modulation of innate immunity will improve replication of these tumor-selective viruses. More recently, he has elucidated how specific microRNAs (miR-128 and miR-451) regulate cellular target transcripts to permit tumor cell self-renewal and invasion into brain. He has been PI of three multi-institutional clinical trials of gene-, viral-therapies for malignant gliomas, has been permanent member of NIH study sections (NCI DT and NCI P01-D clinical studies), has been a member of the federal recombinant DNA Advisory Committee (RAC/OBA) and is currently a member of the NINDS Scientific Advisory Council. In 2013, he was elected Vice-President of the Society for Neuro-Oncology (SNO). In 2015, he was elected President of SNO. He is currently Treasurer of the American Academy of Neurological Surgery and is Chair of the Research Committee for the Society of Neurological Surgery. He also serves on the scientific advisory board of several foundations (Sontag, American Brain Tumor Association). He received The Grass Award in 2007, the Farber Award in 2008 and the Bittner Award in 2013. He was elected to the American Society for Clinical Investigation (2005), is an AAAS fellow (2005) and was also elected to the National Academy of Medicine (formerly Institute of Medicine) in 2014. He also has served on multiple editorial boards and is the current Tumor Section Editor for Neurosurgery. He was on the editorial board of Journal of Neurosurgery from 2005 until 2012.