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SELECTBIO Conferences Emerging Themes and Technologies in Tissue Engineering and Bioprinting

Fabien Guillemot's Biography

Fabien Guillemot, CEO, Poietis

Dr. Fabien Guillemot is the founder of Poietis, a bioprinting company which harnesses the Laser-Assisted Bioprinting technology to fabricate complex and customized tissues for regenerative medicine and pharmaceutical applications. He obtained his PhD in Materials Science in 2000 from the National Institute for Applied Sciences (Rennes, France). He was appointed in 2005 Senior Researcher at the National Institute for Health and Medical Research (INSERM, France). He initiated and led till 2014 the project Tissue Engineering Assisted by Laser (TEAL) which aimed at developing laser-assisted technologies for fabricating artificial tissues into which cells are organized into defined 3D micro-environments. Dr. Guillemot is the author of more than 50 articles in peer-reviewed journals and about 40 invited conferences.

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4D Bioprinting: A New Paradigm for Engineering Complex Tissues

Tuesday, 10 February 2015 at 09:00

Add to Calendar ▼2015-02-10 09:00:002015-02-10 10:00:00Europe/London4D Bioprinting: A New Paradigm for Engineering Complex

Dealing with tissue complexity and reproducing the functional anisotropy of human tissues remain a puzzling challenge for tissue engineers. Emergence of the biological functions results from dynamic interactions between cells, and with extracellular matrix. The important literature showing that cell fate (migration, polarization, proliferation…) is triggered by biochemical and mechanical signals arising from cell microenvironment suggests that tissue formation obeys to short range orders without reference to a global pattern. In that context, the winning tissue engineering strategy might rely on controlling tissue organization at the cell level. Emerging during the last decade, Bioprinting has been defined as “the use of computer-aided transfer processes for patterning and assembling living and non-living materials with a prescribed 2D or 3D organization in order to produce bio-engineered structures serving in regenerative medicine, pharmacokinetic and basic cell biology studies”. From a technological point of view, the Laser-Assisted Bioprinting (LAB) technology has been developped as an alternative method to inkjet and bioextrusion methods, thereby overcoming some of their limitations (namely clogging of print heads or capillaries) to pattern living cells and biomaterials with a micron-scale resolution. By harnessing this high printing resolution, we observe that tissue self-organization over time depends on the cell patterns initially printed by LAB, as well as cell types. To engineer complex tissues, we then emphasize the need to consider the spatio-temporal dynamics of tissue self-organization when designing blueprints.

Add to Calendar ▼2015-02-09 00:00:002015-02-10 00:00:00Europe/LondonEmerging Themes and Technologies in Tissue Engineering and