Hugo Gutierrez de Teran's Biography

Hugo Gutierrez de Teran, Senior Researcher, Uppsala University

• PhD in Health Sciences and Molecular modeling (Pompeu Fabra University, Barcelona, 2004, with Ferran Sanz).
• Postdoctoral fellow: Uppsala University (2006-08, with Johan Åqvist)
• Head, Bioinformatics Unit 2007-2012 (Public Foundation of Genomic Medicine of Galicia, Santiago University Hospital, Spain),
• Visiting researcher, The Scripps Research institute (2012, with Ray Stevens).
• Senior researcher, Uppsala University (2013-present)

Since my PhD I have specialized in Computational Chemistry and Structural Bioinformatics, mostly applied to Drug Design projects, including several collaborations with the pharmaceutical industry. I have co-authored almost 50 scientific publications, including reviews and book chapters. I am actually leading a team of 7 people (4 postdocs), mainly devoted to the characterization and ligand design of G-protein coupled receptors (see http://gpcr-modsim.org). We are also deeply interested on the use of free energy calculations in drug design and biochemical characterization of biological targets. In this presentation I will focus on our recent efforts in introducing free energy calculations in the characterization of GPCRs, and present some successful examples of computer-aided ligand design in this field.