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SELECTBIO Conferences 3D-Printing and Biofabrication 2020

Joyce Wong's Biography



Joyce Wong, Professor of Biomedical Engineering and Materials Science & Engineering, Boston University

Dr. Joyce Y. Wong (Fellow AAAS, AIMBE, BMES) is a Professor of Biomedical Engineering and Materials Science & Engineering, and a College of Engineering Distinguished Faculty Fellow at Boston University. Her research is in the area of developing biomaterials for the early detection and treatment of disease. Her current projects include bioengineered patches for congenital heart defects in pediatric patients, targeted ultrasound theranostic agents to treat abdominal surgical adhesions, and targeted nanoparticle magnetic resonance imaging contrast agents for early detection of cardiovascular disease. She has published over 100 peer-reviewed publications, 11 pending or issued patents (is a graduate of the NSF I-CORPS program), and has mentored over 100 trainees. In 2017 she received the Charles DeLisi Distinguished Lecture and Award, the highest honor in Boston University’s College of Engineering. She is on the editorial board of several journals and in 2017 was a Volume Organizer for the Materials Research Society Bulletin. She is Associate Editor of the Journal of Biomedical Materials (Institute of Physics). In 2014, as the Inaugural Director of a Boston University Provost Initiative promoting women in STEM at all levels, she launched ARROWS (Advance, Recruit, Retain & Organize Women in STEM). In 2018, she received the Advocate of the Year AWARD from BU GWISE (Graduate Women in Science and Engineering).

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Extracellular Matrix Alloys For Vascular Tissue Engineering

Monday, 17 August 2020 at 17:00

Add to Calendar ▼2020-08-17 17:00:002020-08-17 18:00:00Europe/LondonExtracellular Matrix Alloys For Vascular Tissue Engineering3D-Printing and Biofabrication 2020 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com

To engineer and build tissues, one requires an understanding of key relationships between cell behavior and the underlying substrate. In native tissues, extracellular matrix proteins are in the form of fibrous networks, sheets, and fibers. Over the past few years, we have been investigating the role of composition and processing conditions of various extracellular matrix fibers and alloy fibers on mechanical properties and biological properties. These fibers are also critical components of tissues such as blood vessels. We have also determined the role of mechanical strain on binding of different antibodies and peptide-functionalized contrast agents to these fibers. Importantly, we discovered that composition can be tuned to stabilize extracellular matrix proteins in fiber forms, which is especially useful with compositions where it is difficult to process the proteins into fibers. Through an integrated computational and experimental approach, we have discovered relationships between hydrophobicity and protein fiber forming capability and stability. Moreover, we have verified that the protein alloy fibers support cell adhesion and allow one to tune the mechanical properties of the fiber. This is of significance as the mechanical properties of the substrate play an important role in modulating cell behavior, e.g. cell migration and proliferation.


Add to Calendar ▼2020-08-17 00:00:002020-08-18 00:00:00Europe/London3D-Printing and Biofabrication 20203D-Printing and Biofabrication 2020 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com