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SELECTBIO Conferences Exosomes & Single Cell Analysis Summit

David Palmlund's Biography

David Palmlund, Technical Sales Engineer, Microtrac

David Palmlund is a Technical Sales Engineer with Particle Metrix. He has over 10 years of experience in particle characterization with a focus on Dynamic Imaging Particle Analysis, and more recently, Particle Tracking Analysis. Prior to working with Particle Metrix, Dave worked at Fluid Imaging Technologies as a Product Manager where he managed the development and launch of new additions to their line of particle analyzers. Dave received his undergraduate degree in biology from Bates college and his MBA from the University of Southern Maine. In addition to particle characterization, Dave also has extensive experience in the fields of analytical chemistry and pharmaceutical R&D.

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Particle Tracking Analysis (PTA): Size and Charge Fingerprints of Exosomes

Friday, 19 September 2014 at 16:00

Add to Calendar ▼2014-09-19 16:00:002014-09-19 17:00:00Europe/LondonParticle Tracking Analysis (PTA): Size and Charge Fingerprints of ExosomesExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California,

In the field of nanoparticle characterization, zeta potential has long been known as measure for stability and particle-particle interactions and is a physical-chemical parameter. However, the characterization of low concentrated nanoparticle suspensions, such as exosomes, is challenging.
Particle Tracking Analysis (PTA) is a technique where single particles of the sample are visualized and traced. By analysis of the particle traces, the PTA device (ZetaView®, Particle Metrix, Germany) performs the measurement of particle size, concentration and zeta potential of exosomes in one experiment. As the zeta potential is affected by pH and ionic strength, even more information about the sample can be gained by variation of buffer composition, resulting in discrete charge fingerprints. We utilize the advantages of PTA with emphasis on practical aspects relevant for exosome characterization. Potential applications, such as monitoring of pH sensitive exosome-exosome interactions in combination with multiparameter characterization will be discussed on selected examples.

Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonExosomes and Single Cell Analysis SummitExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California,