| Conferences \ Circulating Biomarkers World Congress 2017 \ Circulating Biomarkers: Cell-Free Nucleic Acids, Proteins and Rare Circulating Cells \ Agenda \ Roopali Gandhi |
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Validation of miRNA as Diagnostic and Prognostic Biomarkers for Multiple SclerosisMonday, 20 March 2017 at 14:00  Add to Calendar ▼2017-03-20 14:00:002017-03-20 15:00:00Europe/LondonValidation of miRNA as Diagnostic and Prognostic Biomarkers for Multiple SclerosisSELECTBIOenquiries@selectbiosciences.comMultiple sclerosis (MS) is an autoimmune disease characterized by progressive neuronal demyelination, resulting in varying degrees of disability over time. MS is usually diagnosed based on the clinical symptoms and Magnetic Resonance Imaging (MRI) analysis. There is an urgent need to find blood-based biomarker for MS disease diagnosis, disease stage, and to study treatment response. Following a two-year discovery and validation phase, we performed a multi-center international validation study aiming to investigate the potential use of miRNA expression as non-invasive biomarkers for MS disease diagnosis, disease stage, and association with MS clinical parameters. We found miRNAs that were differentially expressed in MS patients and associated with its clinical parameters. These miRNAs of interest exhibit clear biological significance in MS pathophysiology and are promising candidates for further exploration of their potential use in developing predictive diagnostic, prognostic, or therapeutic tools for MS. |
Add to Calendar ▼2017-03-20 00:00:002017-03-21 00:00:00Europe/LondonCirculating Biomarkers: Cell-Free Nucleic Acids, Proteins and Rare Circulating CellsSELECTBIOenquiries@selectbiosciences.com
