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SELECTBIO Conferences Genome Engineering

Tudor Fulga's Biography

Tudor Fulga, Associate Professor of Genome Biology, University of Oxford

Tudor Fulga obtained his PhD from the European Molecular Biology Laboratory (EMBL), and subsequently received training at Harvard Medical School, first as a postdoctoral fellow and later as an Instructor in Cell Biology. In 2011/2012, he joined the Weatherall Institute of Molecular Medicine (WIMM) in Oxford as a Group Leader and MRC senior research fellow. In 2014 he was appointed Associate Professor of Genome Biology at Radcliffe Department of Medicine, University of Oxford. As a graduate student, Fulga initially studied the process of protein translocation across the ER with Irmgard Sinning, and later the cellular events controlling invasive cell migration with Pernille Rorth. He later joined the laboratory of Mel Feany at Harvard Medical School as a postdoctoral fellow, where he investigated the molecular mechanisms underlying neurodegeneration in Alzheimer’s disease. Subsequently, he was appointed Instructor in Cell Biology at Harvard Medical School and together with his advisor David Van Vactor has pioneered a highly versatile in vivo transgenic technology for conditional knockdown of miRNAs with precise spatial-temporal resolution. At the University of Oxford his research is focused on deciphering the role of non-coding regulatory RNAs in development and diseases, and uncovering the molecular mechanisms governing microRNA target recognition and silencing. In a parallel direction, his group aims to repurpose the functionality contained within RNA molecules to develop logic-function molecular devices capable of rewiring cellular behavior. His team routinely employs genome engineering strategies (TALEN, CRISPR/Cas9) to answer complex biological and disease questions in a variety of model systems, while continuing to develop novel dimensions of these technologies aimed to advance their in vivo versatility.

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Deciphering miRNA-target Regulation by Site-specific Genome Engineering

Thursday, 8 October 2015 at 15:30

Add to Calendar ▼2015-10-08 15:30:002015-10-08 16:30:00Europe/LondonDeciphering miRNA-target Regulation by Site-specific Genome EngineeringGenome Engineering in Hanover, GermanyHanover,

Central to understanding cellular networks regulated by miRNAs is identification of their primary targets in vivo. We have developed a powerful genome engineering experimental platform, which enables rapid interrogation of physiologically relevant miRNA response elements in intact biological systems.

Add to Calendar ▼2015-10-07 00:00:002015-10-08 00:00:00Europe/LondonGenome EngineeringGenome Engineering in Hanover, GermanyHanover,