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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics 2020

Albert Folch's Biography



Albert Folch, Professor of Bioengineering, University of Washington

Albert Folch received his BSc in physics from the University of Barcelona (UB), Spain, in 1989. In 1994, he received his PhD in surface science and nanotechnology from the UB’s Physics Dept. During his PhD he was a visiting scientist from 1990–91 at the Lawrence Berkeley Lab working on AFM under Dr. Miquel Salmeron. From 1994–1996, he was a postdoc at MIT developing MEMS under the advice of Martin Schmidt (EECS) and Mark Wrighton (Chemistry). In 1997, he joined the laboratory of Mehmet Toner as a postdoc at Harvard’s Center for Engineering in Medicine to apply soft lithographic methods to tissue engineering. He has been at Seattle’s UW BioE since June 2000 where he is now a full Professor, accumulating over 8,700 citations (averaging >97 citations/paper over his whole UW career). In 19 years, he has supervised 16 postdocs (19% of whom have reached faculty rank), 11 Ph.D. students (27% of whom have reached faculty rank), 17 M.S. students, and >40 undergraduates. His lab works at the interface between microfluidics and cancer. In 2001 he received a NSF Career Award and in 2014 he was elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows (Class of 2015). He serves on the Advisory Board of Lab on a Chip since 2006. Albert Folch is the author of four books, including “Introduction to BioMEMS”, a textbook now adopted by more than 88 departments (81 universities) in 18 countries (including 40 universities in the U.S. alone), and other scientific dissemination books. Since 2007, the lab runs a celebrated outreach art program called BAIT (Bringing Art Into Technology) which has produced seven exhibits, a popular resource gallery of >2,000 free images related to microfluidics and microfabrication, and a YouTube channel that plays microfluidic videos with music which accumulates ~149,000 visits since 2009.

Albert Folch Image

Microfluidics for Interrogating Intact-Tumor Biopsies

Monday, 28 September 2020 at 14:00

Add to Calendar ▼2020-09-28 14:00:002020-09-28 15:00:00Europe/LondonMicrofluidics for Interrogating Intact-Tumor BiopsiesLab-on-a-Chip and Microfluidics 2020 in Virtual ConferenceVirtual ConferenceSELECTBIOenquiries@selectbiosciences.com

Cancer remains a major healthcare challenge worldwide. It is now well established that cancer cells constantly interact with fibroblast cells, endothelial cells, immune cells, signaling molecules, and the extracellular matrix in the tumor microenvironment (TME). Present tools to study drug responses and the TME have not kept up with drug testing needs. The number of clinical trials of combination therapies has been climbing at an unsustainable rate, with 3,362 trials launched since 2006 to test PD-1/PD-L1-targeted monoclonal antibodies alone or in combination with other agents. We have developed a microfluidic platform (called Oncoslice) for the delivery of multiple drugs with spatiotemporal control to live tumor biopsies, which retain the TME. We have developed the use of Oncoslice for the delivery of small-molecule cancer drug panels to glioblastoma (GBM) xenograft slices as well as to slices from patient tumors (GBM and colorectal liver metastasis). In addition, we have developed a precision slicing methodology that allows for producing large numbers of cuboidal micro-tissues (“cuboids”) from a single tumor biopsy. We have been able to trap cuboids in arrays of microfluidic traps in a multi-well platform. This work will potentially allow for the high-throughput application of drugs to intact human tumor tissues.


Add to Calendar ▼2020-09-28 00:00:002020-09-30 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics 2020Lab-on-a-Chip and Microfluidics 2020 in Virtual ConferenceVirtual ConferenceSELECTBIOenquiries@selectbiosciences.com