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SELECTBIO Conferences MetaboMeeting 2015

Mike Murphy's Biography

Mike Murphy, Group Leader, Medical Research Council

Mike Murphy received his BA in chemistry at Trinity College, Dublin in 1984 and his PhD in Biochemistry at Cambridge University in 1987. After stints in the USA, Zimbabwe, and Ireland he took up a faculty position in the Biochemistry Department at the University of Otago, Dunedin, New Zealand in 1992. In 2001 he moved to the MRC Mitochondrial Biology Unit in Cambridge, UK (then called the MRC Dunn Human Nutrition Unit) where he is a group leader. His research is concerned with all aspects of mitochondrial function and dysfunction. Currently his special interests are in targeting small molecules such as antioxidants to mitochondria, and in understanding how modifications to the thiol status of mitochondrial proteins contributes to oxidative damage and redox signalling.

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Succinate Toxicity in Reperfusion Injury

Wednesday, 9 December 2015 at 14:00

Add to Calendar ▼2015-12-09 14:00:002015-12-09 15:00:00Europe/LondonSuccinate Toxicity in Reperfusion Injury MetaboMeeting 2015 in Cambridge, UKCambridge,

Succinate accumulates in ischaemia due to reversal of mitochondrial complex II. Then, upon reperfusion this succinate can drive reverse electron transport at complex I and thereby produce damaging ROS.

Add to Calendar ▼2015-12-07 00:00:002015-12-09 00:00:00Europe/LondonMetaboMeeting 2015MetaboMeeting 2015 in Cambridge, UKCambridge,