Chemogenomic Approaches to Spatiotemporal Regulation of HDAC ActivityWednesday, 27 January 2016 at 11:45 Add to Calendar ▼2016-01-27 13:44:002016-01-27 14:44:00Europe/LondonDay Two Afternoon SessionEpigenetics in Drug Discovery in Cambridge, UKCambridge, UKSELECTBIOenquiries@selectbiosciences.com We present a novel and generalizable approach that enables high-resolution, optical control of histone deacetylases based on photochromic inhibitors using visible light. The presented compounds have high isoform selectivity and exhibit a differential activity of three orders of magnitude. Day Two Afternoon SessionWednesday, 27 January 2016 at 13:44 Add to Calendar ▼2016-01-27 13:44:002016-01-27 14:44:00Europe/LondonDay Two Afternoon SessionEpigenetics in Drug Discovery in Cambridge, UKCambridge, UKSELECTBIOenquiries@selectbiosciences.com |