NanoVelcro-Based Single-Cell Genomics Verifies Surrogacy of Circulating Tumor Cells for Solid TumorThursday, 18 September 2014 at 11:15  Add to Calendar ▼2014-09-18 11:15:002014-09-18 12:15:00Europe/LondonNanoVelcro-Based Single-Cell Genomics Verifies Surrogacy of Circulating Tumor Cells for Solid TumorExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.comOur team at UCLA has demonstrated a highly efficient, inexpensive CTC assay (known as NanoVelcro Chips) capable of detecting and isolating circulating tumor cells (CTCs) in blood samples collected from metastatic cancer patients. In addition to conducting CTC enumeration, we have been exploring the use of NanoVelcro Chips to isolate single CTCs without contamination by white blood cells (WBCs). The individually isolated CTCs can then be subjected to molecular analysis by RT-PCR and next-generation sequencing, providing insights into tumor biology and heterogeneity and identify driver mutations that responsible to malignant transformation of cancer. Moreover, the molecular profiling of CTCs may identify novel biomarkers that could guide the choice of therapies for individual patients as well as facilitate the development of new drugs. |
Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonExosomes and Single Cell Analysis SummitExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
