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SELECTBIO Conferences Tissue Engineering

Matthew Applegate's Biography

Matthew Applegate, Research Fellow, Ultrafast Nonlinear Optics and Biophotonics Laboratory, Tufts University

Matthew Applegate is currently research fellow at Tufts University under the mentorship of Fiorenzo Omenetto. His work investigates ways that light interacts with biomaterials to image, treat, diagnose, and prevent disease. His previous work at the Wellman Center for Photomedicine focused on using Optical Coherence Tomography to map lung cancer.

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3D Micromachining in Silk Hydrogels

Friday, 18 March 2016 at 12:00

Add to Calendar ▼2016-03-18 12:00:002016-03-18 13:00:00Europe/London3D Micromachining in Silk

Silk, a biodegradable and biocompatible natural polymer, can be formed into transparent hydrogels ideal for tissue engineering applications.  Exposure to focused ultra-short pulses of near infrared light results in multi-photon absorption within the focal volume of the beam leading to the formation of voids, without the need for exogenous photo-initiators.  The high transparency of the gel and the low pulse energies used enable the formation of micro-voids nearly 1 cm below the surface of the gel.  These voids can then be linked together into larger structures that can be used to guide cells within the gel both in vitro and in vivo for tissue engineering applications.

Add to Calendar ▼2016-03-17 00:00:002016-03-18 00:00:00Europe/LondonTissue