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SELECTBIO Conferences Biofabrication & Biomanufacturing Europe 2019

John Hundley Slater's Biography



John Hundley Slater, Associate Professor of Biomedical Engineering, University of Delaware

Dr. Slater received a Bachelor of Science in Mechanical Engineering from the University of North Carolina at Charlotte in 2001, graduating Magna Cum Laude, where he was a recipient of the Danielson Endowment Scholarship as well as the James S. Jones Memorial Scholarship. He received a PhD in Biomedical Engineering with a Graduate Portfolio Degree in Nanoscience and Nanotechnology from the University of Texas at Austin in 2008 where he was a National Science Foundation Graduate Research Fellow, Department of Biomedical Engineering Tom Collins Fellow, and College of Engineering Thrust Fellow. He was a National Institutes of Health Nanobiology Postdoctoral Training Fellow and a Howard Hughes Medical Institute Postdoctoral Training Fellow in Bioengineering at Rice University until 2012 and a Research Scientist in Biomedical Engineering at Duke University until 2013. He is currently an Associate Professor of Biomedical Engineering at the University of Delaware and an Affiliated Faculty in the Department of Materials Science and Engineering and the Delaware Biotechnology Institute. His research interests include biomimetic materials, mechanobiology, microenvironmental control over cell fate, in vitro microfluidic models, and cell and tissue engineering.

John Hundley Slater Image

Chairman's Welcome and Introduction to the Conference

Thursday, 20 June 2019 at 08:45

Add to Calendar ▼2019-06-20 11:45:002019-06-20 12:45:00Europe/LondonScale-Encompassing Vascular Models via Laser-Induced Hydrogel DegradationBiofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

Scale-Encompassing Vascular Models via Laser-Induced Hydrogel Degradation

Thursday, 20 June 2019 at 11:45

Add to Calendar ▼2019-06-20 11:45:002019-06-20 12:45:00Europe/LondonScale-Encompassing Vascular Models via Laser-Induced Hydrogel DegradationBiofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

In the United States, one of every three deaths is attributed to cardiovascular disease (CD). To address these alarming statistics, in vitro vessels-on-a-chip could be a useful tool for modeling CD and developing and testing potential drug candidates. While many engineering approaches can generate large diameter vessels, the ability to generate vessels in the arteriole to capillary size range is non-trivial. Additionally, many existing approaches to engineer microvasculature are limited in their ability to generate repeatable networks with respect to vascular scale and architecture, or to generate 3D biomimetic networks. To address these limitations, we developed a laser-induced hydrogel degradation (LIHD) technique to fabricate biomimetic, perfusable, endothelialized µfluidic networks in both synthetic and natural hydrogels. LIHD allows generation of vascular features over a 100-fold range from 3 to 300 µm in diameter, encompassing arteriole to capillary sized vessels, and enables tailoring of the cellular microenvironment to fit the desired disease modeling application of in vitro vascularized constructs.


Add to Calendar ▼2019-06-20 00:00:002019-06-21 00:00:00Europe/LondonBiofabrication and Biomanufacturing Europe 2019Biofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com