| Conferences \ Circulating Biomarkers World Congress 2017 \ Circulating Biomarkers: Cell-Free Nucleic Acids, Proteins and Rare Circulating Cells \ Agenda \ Stacey Gifford |
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Separation of Circulating Biomarkers Using nanoDLD Chip TechnologyMonday, 20 March 2017 at 15:00  Add to Calendar ▼2017-03-20 15:00:002017-03-20 16:00:00Europe/LondonSeparation of Circulating Biomarkers Using nanoDLD Chip TechnologySELECTBIOenquiries@selectbiosciences.comIsolation of exosomes and circulating cell-free DNA has been an ongoing challenge in the development of the liquid biopsy. By scaling deterministic lateral displacement arrays to the nanoscale, we have fabricated a chip-based technology enabling the separation of particles down to 20 nm. We have demonstrated the ability to sub-fractionate exosomes and DNA by size and measure their size distribution on-chip. Additionally, we can label exosomal surface markers and quantify the distribution of these proteins within a population of exosomes, enabling size and surface marker correlation. Our aim is to scale this technology in order to provide both a large-scale preparative and diagnostic tool for exosome and cfDNA isolation and detection. |
Add to Calendar ▼2017-03-20 00:00:002017-03-21 00:00:00Europe/LondonCirculating Biomarkers: Cell-Free Nucleic Acids, Proteins and Rare Circulating CellsSELECTBIOenquiries@selectbiosciences.com
