May Griffith,
Professor and Caroline Durand Foundation Research Chair in Cellular Therapy,
University of Montreal
May Griffith is Professor of Ophthalmology at the University of Montreal, and holds the Caroline Durand Foundation Research Chair in Cellular Therapy. She is also a co-founder of UAB Ferentis, an award-winning start-up spun off from the EuroNanomedicine project “I-CARE”. MG’s current research is in the development of biomimetic materials based on collagen and its analogs, for translational regenerative medicine applications. She has led a team that developed the world's first cell-free corneal implants that successfully promoted regeneration of corneal tissues and nerves. She continues to work on improvements for use in corneas with more severe pathologies that are currently deemed not treatable, by developing new materials, incorporation of nano-delivery systems and surface patterning techniques. The biomaterials developed are also being tested for use in theranostics, and as pro-regeneration scaffolds in other organ systems in collaboration with other researchers.
Biomimetic Collagen-Like Hydrogels: From In Vitro Testing to Regenerative Medicine
Wednesday, 18 October 2017 at 08:30
Add to Calendar ▼2017-10-18 08:30:002017-10-18 09:30:00Europe/LondonBiomimetic Collagen-Like Hydrogels: From In Vitro Testing to Regenerative MedicineBioprinting and 3D Printing in the Life Sciences Europe in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
The body’s extracellular matrix (ECM) modulates both organ development and its repair and regeneration. Collagen is a major component of the ECM and we have shown that a recombinantly produced version of human collagen in form of cell-free hydrogel implants successfully promoted regeneration of the human cornea in clinical trials. These implants were fabricated by 3D moulding. However, recombinant human collagen like native collagen is a large protein and not easily processed for fabrication into implants. We have therefore developed collagen-like peptide-based analogs. These analogs can also be moulded into implants and their performance in pre-clinical large animal models shows equivalence in function. However, they are readily synthesized, easy to functionalize chemically as well as physically, the latter by micro- and nano-patterning.
Add to Calendar ▼2017-10-17 00:00:002017-10-18 00:00:00Europe/LondonBioprinting and 3D Printing in the Life Sciences EuropeBioprinting and 3D Printing in the Life Sciences Europe in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2017-10-18 08:30:002017-10-18 09:30:00Europe/LondonBiomimetic Collagen-Like Hydrogels: From In Vitro Testing to Regenerative MedicineBioprinting and 3D Printing in the Life Sciences Europe in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
