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SELECTBIO Conferences Exosomes & Liquid Biopsies Europe 2018

Tomoko Yoshino's Biography



Tomoko Yoshino, Professor, Tokyo University of Agriculture and Technology

Tomoko Yoshino is Professor of Biotechnology at Tokyo University of Agriculture and Technology. She received her Doctor of Engineering degree in Biotechnology from Tokyo University of Agriculture and Technology in 2005. After studying as a Research Associate in Waseda University, she was adopted for Associate Professor of tenure-track system at Tokyo University of Agriculture and Technology. She was promoted to Associate Professor with tenure in 2011 and Professor in 2018. Her present research is focused on studying development of novel techniques for single cell analysis. She is currently a reader of CREST promotion program supported by the JST (Japan Science and Technology Agency) in the research area “Innovative Technology Platforms for Integrated Single Cell Analysis”. In addition, she also focused on the production of functional materials using genetically engineered microorganism.

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Single-Cell Transcriptome Analysis For Circulating Tumor Cells based on Microcavity Array

Thursday, 25 October 2018 at 14:00

Add to Calendar ▼2018-10-25 14:00:002018-10-25 15:00:00Europe/LondonSingle-Cell Transcriptome Analysis For Circulating Tumor Cells based on Microcavity ArrayExosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

Circulating tumor cells (CTCs) are one of the powerful biomarkers for cancer diagnosis and potential targets for drug discovery. Genetic analysis of CTCs could provide detailed information of cancer patient. However, the recovery of such extremely rare cells from the peripheral blood and the achievement of genetic analysis without loss of CTCs presents a technical challenge. In this presentation, I will introduce several techniques towards single-cell transcriptome analysis for CTCs. Filtration using metal microfilters (microcavity array: MCA) has been used to develop precise CTC recovery technique. Furthermore, recovered cells on the MCA is easily manipulated by encapsulation by photopolymerizable hydrogel using multiple light projection system, resulting in simply manipulate multiple CTCs at a single cell level. The cells were applied RNA-seq analysis, and we investigated single cell gene expression analysis to reveal the cancer-specific transcripts. We believe our system have a potential to apply high-throughput single-CTC analysis and contribute for development of non-invasive cancer diagnosis method.


Add to Calendar ▼2018-10-24 00:00:002018-10-26 00:00:00Europe/LondonExosomes and Liquid Biopsies Europe 2018Exosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com