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SELECTBIO Conferences Biofabrication & Biomanufacturing Europe 2019

João F. Mano's Biography

João F. Mano, Professor Department of Chemistry, CICECO — Aveiro Institute of Materials, University of Aveiro

João F. Mano (CEng, PhD, DSc) is a Full Professor at the Chemistry Department of University of Aveiro, Portugal, where he is directing both the MSc and PhD programs of Biotechnology. He is the founder and director of the COMPASS Research Group, from the Associated Laboratory CICECO – Aveiro Institute of Materials. His research interests include the use of biomaterials and cells cells towards the progress of transdisciplinary concepts to be employed in regenerative and personalised medicine. In particular, he has been applying biomimetic and nano/micro-technology approaches to polymer-based biomaterials and surfaces in order to develop biomedical devices with improved structural and (multi-)functional properties, or in the engineering of microenvironments to control cell behaviour and organization, to be exploited clinically in advanced therapies or in drug screening.

João F. Mano is author of 590+ papers in international journals (20000+ citations, h=72, WoS). He has been part of a series of scientific societies and editorial boards of international journals, and is the Editor-in-Chief of Materials Today Bio (Elsevier). He has been coordinating or involved in many national and European research projects, including Advanced and Proof-of-Concept Grants from the European Research Council.

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Soft Hybrid Units For the Biomanufacture of Tissues For Regenerative Medicine

Friday, 21 June 2019 at 11:15

Add to Calendar ▼2019-06-21 11:15:002019-06-21 12:15:00Europe/LondonSoft Hybrid Units For the Biomanufacture of Tissues For Regenerative MedicineBiofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The

Sophisticated strategies have been proposed to encapsulate cells in micro-compartments using distinct biomaterials, to be explored in bottom-up tissue engineering strategies. We propose distinct enabling technologies that could be used to encapsulate both molecules and cells in geometrically controlled units that could be then assembled into bigger structures. Superhydrophobic surfaces serve as platforms to process basic units of hydrogels in mild conditions, permitting the encapsulation of living cells and other biological cargo with high efficiency. In another strategy, capsules are fabricated using the so-called layer-by-layer technology, where the consecutive layers are well stabilized by electrostatic interactions or other weak forces. By using spherical templates containing cells it is possible to produce liquefied capsules that may entrap viable cells. The presence of solid microparticles inside such capsules offers adequate surface area for adherent cell attachment (with controlled mechanical properties) increasing the biological performance of these hierarchical systems, while maintain both permeability and injectability. The liquid environment allows for a free-organization in the space of the cells towards the formation of new microtissues.

Add to Calendar ▼2019-06-20 00:00:002019-06-21 00:00:00Europe/LondonBiofabrication and Biomanufacturing Europe 2019Biofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The