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SELECTBIO Conferences Extracellular Vesicle-based Dx & Rx Summit

Clayton Deighan's Biography

Clayton Deighan, Regional Sales Director, NanoView Biosciences

Dr. Deighan has been studying circulating biomarkers for eight years, completing his thesis research on circulating tumor cell and extracellular vesicle characterization. He has recently joined NanoView Biosciences, which develops tools for extracellular vesicle characterization, to help realize the potential in these tiny particles.

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Routine Single EV Protein Biomarker Analysis

Thursday, 28 March 2019 at 16:30

Add to Calendar ▼2019-03-28 16:30:002019-03-28 17:30:00Europe/LondonRoutine Single EV Protein Biomarker AnalysisExtracellular Vesicle-based Dx and Rx Summit in Coronado Island, CaliforniaCoronado Island,

One of the major limitations to the realization of the potential in EV biomarkers is the lack of techniques for phenotyping individual EVs. In this presentation we will present the ExoView platform, a new tool for the capture and characterization of EVs from many sources. By coupling a validatable immunoassay for capturing EVs with no prior purification with a sensitive interferometric measurement of single EVs (50+nm) with no additional labeling we separate important populations from the noise.  The secondary analysis by counterstaining for biomarkers of interest can be custom designed by the user allowing for detection of the markers of interest in their research with minimal assay development time.  Example datasets for marker colocalization will be presented for EVs from a variety of sources.

Add to Calendar ▼2019-03-28 00:00:002019-03-28 00:00:00Europe/LondonExtracellular Vesicle-based Dx and Rx SummitExtracellular Vesicle-based Dx and Rx Summit in Coronado Island, CaliforniaCoronado Island,