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SELECTBIO Conferences Organ-on-a-Chip & Tissue-on-a-Chip Europe 2019

Danny van Noort's Biography

Danny van Noort, Associate Professor, Linköping University

I have a MSc in experimental physics from Leiden University, the Netherlands, and a PhD in applied physics from Linköping University, Sweden. My main interests lie on the borderline of physics, engineering and biology, especially, the application of micro and nanotechnology to life science problems, notably organ-on-a-chip. I have held positions at top universities around the world, such as Princeton University, Seoul National University, National University of Singapore working on research topics, such as, biosensors, DNA computing in microfluidics, 3D cell culture in microfluidics, human-on-a-chip, organ-on-a-chip, microfabricated structures, automated liquid handling. I have published more than 50 papers in international journals (5 with cover art). Also, I have presented at more than 40 conferences, including keynote speaker, 70 invited lectures at universities and institutes. 2 of my papers were included in a special edition of Lab on a Chip and Integrative Biology collection of articles on organ-on-chip research. 3 papers have been top 10 most downloaded papers, while 1 of them has had that distinction for 9 months in a row, and another has been awarded 3rd highest cited paper from Singapore.

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Towards Human on a Chip

Wednesday, 19 June 2019 at 16:45

Add to Calendar ▼2019-06-19 16:45:002019-06-19 17:45:00Europe/LondonTowards Human on a ChipOrgan-on-a-Chip and Tissue-on-a-Chip Europe 2019 in Rotterdam, The NetherlandsRotterdam, The

In this presentation I will introduce our established 3D cell culture chip (or OoC), showing its performance compared to 2D cell cultures, using primary rat liver cells and C3A cell line. From there, an 8-channel human liver IC50 chip will be presented, showing a good drug toxicity correlation to animal models. This means this chip is the first step towards predictive assays. Following, I will show, with our endocrine system on a chip, the effect of L-cells on the insulin production in beta-cells. This is a 2-channel connected system. By changing the concentration of glucose, there will be a change in the dynamics of insulin production. Finally, a human-on-a-chip, represented by a 4-channel device with lung, liver, kidney and fat cells, will be presented. Local release of growth factors and a base medium ensure for highly functional cell cultures.

Add to Calendar ▼2019-06-18 00:00:002019-06-19 00:00:00Europe/LondonOrgan-on-a-Chip and Tissue-on-a-Chip Europe 2019Organ-on-a-Chip and Tissue-on-a-Chip Europe 2019 in Rotterdam, The NetherlandsRotterdam, The