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SELECTBIO Conferences 3D-Printing in the Life Sciences

Ruogang Zhao's Biography



Ruogang Zhao, Assistant Professor, SUNY Buffalo

Dr. Ruogang Zhao is an Assistant Professor in the Department of Biomedical Engineering at the State University of New York at Buffalo. He received his PhD in biomaterials and biomedical engineering from the University of Toronto. He was a postdoctoral fellow in biological physics at the Johns Hopkins University before moving to Buffalo. Through combining advanced biofabrication technologies and biomechanics, he has developed a unique research program to address the unmet need to model the physiology and pathology of mechanosensitive tissues. During his Ph.D. training, he received the prestigious Heart and Stroke Foundation of Canada Doctoral Research Award. He has been recently nominated to receive the 2019 Young Innovators Award of Cellular and Molecular Bioengineering.

Ruogang Zhao Image

Force Sensing Microtissue Arrays For Disease Modeling and Drug Discovery in Fibrosis and Abnormal Clotting

Tuesday, 15 October 2019 at 10:00

Add to Calendar ▼2019-10-15 10:00:002019-10-15 11:00:00Europe/LondonForce Sensing Microtissue Arrays For Disease Modeling and Drug Discovery in Fibrosis and Abnormal Clotting3D-Printing in the Life Sciences in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com

This talk will describe our recent development of microtissue array systems with tissue morphogenesis and force sensing capabilities. These mechanically-active 3D microtissue models have been shown as powerful tools for disease modeling and drug discovery. Using microfabricated arrays of flexible micropillars, we generated lung alveolar-like, contractile microtissues for the screening of anti-fibrosis drugs. We provided proof of principle for using this fibrotic tissue array for multi-parameter, phenotypic analysis of the therapeutic efficacy of two anti-fibrosis drugs recently approved by the FDA. We also developed force sensor-coupled collagen microtissues for the modeling of normal and abnormal blood clotting under shear flow. Studies with antagonists and diseased patient plasma demonstrate the ability of the system to assay clot biomechanics associated with both common antiplatelet treatments and bleeding disorders.


Add to Calendar ▼2019-10-14 00:00:002019-10-15 00:00:00Europe/London3D-Printing in the Life Sciences3D-Printing in the Life Sciences in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com