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SELECTBIO Conferences 3D-Culture, Organoids & Tox Screening Europe 2019

Robert Vries's Biography

Robert Vries, CEO, Hubrecht Organoid Technology (HUB)

Robert received his PhD in Biochemistry form the Leiden University Medical Center on a molecular study of oncogenic transformation. He subsequently moved to Stanford University (USA) to do his Post Doc studying neural stem cells. Upon his return to the Netherlands he continued the study of adult stem cells in the group of Prof Hans Clevers at the Hubrecht Institute in The Netherlands.
In the group of Hans Clevers he was part of the team that developed the breakthrough technology that allowed the expansion of adult stem cells. The so-called Organoid Technology became the basis of the company ‘Hubrecht Organoid Technology’ (HUB) of which he is currently the CEO.

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Organoids, A Preclinical Patient Population

Thursday, 13 June 2019 at 17:00

Add to Calendar ▼2019-06-13 17:00:002019-06-13 18:00:00Europe/LondonOrganoids, A Preclinical Patient Population3D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The

Key to the improvement of drug development and disease modeling is a preclinical model that represents patients. We previously developed an adult stem cells derived culture system that allowed for the genetically and phenotypically stable expansion of human epithelial cells. The Organoids derived from a variety of organs such as lung, liver, pancreas, breast, etc, are a powerful tool to study Cancer, Cystic Fibrosis and other diseases. Recent studies show that the in vitro response to drug treatments tested organoids correlate with the clinical outcome of the patient from which the organoid was derived.  Therefore, the organoids appear to faithfully represent a patient in the lab.  The scalability of the organoids potentially provides a novel approach to screening in early discovery, drug development as well as predictive diagnostics.

Add to Calendar ▼2019-06-13 00:00:002019-06-14 00:00:00Europe/London3D-Culture, Organoids and Tox Screening Europe 20193D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The