Robert received his PhD in Biochemistry from the Leiden University Medical Center where he studied oncogenic cell transformation in the lab of Prof. van de Eb. He subsequently moved to Stanford University (USA) to pursue his post-doctoral career on neural stem cells. Upon his return to the Netherlands, he joined the group of Prof. Hans Clevers at the Hubrecht Institute where he was involved in the development of the breakthrough “Organoid Technology” that allows the expansion of adult stem cells and the development of “mini-organs in a dish”. Rob is currently CEO of HUB, which was founded to further develop and refine the Organoid Technology.
Organoids, A Preclinical Patient Population
Thursday, 13 June 2019 at 17:00
Add to Calendar ▼2019-06-13 17:00:002019-06-13 18:00:00Europe/LondonOrganoids, A Preclinical Patient Population3D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Key to the improvement of drug development and disease modeling is a preclinical model that represents patients. We previously developed an adult stem cells derived culture system that allowed for the genetically and phenotypically stable expansion of human epithelial cells. The Organoids derived from a variety of organs such as lung, liver, pancreas, breast, etc, are a powerful tool to study Cancer, Cystic Fibrosis and other diseases. Recent studies show that the in vitro response to drug treatments tested organoids correlate with the clinical outcome of the patient from which the organoid was derived. Therefore, the organoids appear to faithfully represent a patient in the lab. The scalability of the organoids potentially provides a novel approach to screening in early discovery, drug development as well as predictive diagnostics.
Add to Calendar ▼2019-06-13 00:00:002019-06-14 00:00:00Europe/London3D-Culture, Organoids and Tox Screening Europe 20193D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2019-06-13 17:00:002019-06-13 18:00:00Europe/LondonOrganoids, A Preclinical Patient Population3D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
