Establishing Saccharomyces Boulardii as an In-Gut Biomanufacturing PlatformTuesday, 22 March 2022 at 13:00  Add to Calendar ▼2022-03-22 13:00:002022-03-22 14:00:00Europe/LondonEstablishing Saccharomyces Boulardii as an In-Gut Biomanufacturing PlatformBiofabrication and Biomanufacturing 2022 in BostonBostonSELECTBIOenquiries@selectbiosciences.comSaccharomyces boulardii is a widely used yeast probiotic, demonstrating effectiveness against various gastrointestinal disorders. S. boulardii is therefore a promising chassis for development of personalized engineered probiotic medicines. In this talk, I will discuss our lab’s recent progress in optimizing both small molecule and peptide biosynthesis in this strain, as well as our efforts to enhance S. boulardii’s in vivo residence time. Last, I will discuss some new work from our lab focusing on the development of gut- and small-molecule inducible promoters for this organism. Taken together, this work establishes S. boulardii as a genetically tractable commensal fungus and demonstrates the delivery of therapeutics during colonization. |
Add to Calendar ▼2022-03-21 00:00:002022-03-22 00:00:00Europe/LondonBiofabrication and Biomanufacturing 2022Biofabrication and Biomanufacturing 2022 in BostonBostonSELECTBIOenquiries@selectbiosciences.com
