Su Ryon Shin,
Assistant Professor of Medicine,
Harvard Medical School and Brigham and Women’s Hospital
Su Ryon Shin, PhD, received a doctoral degree from Hanyang University, South Korea. In 2010, she joined the staff at the Brigham and Harvard Medical School (HMS) as a postdoctoral research fellow in the Division of Engineering in Medicine. Shin was promoted to instructor at HMS in 2014. Today, Shin is an Assistant professor of medicine at the Brigham and HMS. Her research focuses on developing micro- and nano-technologies to control cellular behavior, with particular emphasis on developing micro-scale biomaterials and engineering systems for various biomedical applications. Also, Dr. Shin has been developing integrated organs-on-chip systems with built-in biosensors. During her research period at the Brigham, Dr. Shin has been extremely prolific in her work, which has resulted in several funded grants by National Institutes of Health, American Heart Association, Air Force Office of Sponsored Research, Toyota Motor Corporation, and the Advanced Regenerative Manufacturing Institute of the U.S. Department of Defense, etc. In addition, she has published over 148 papers in peer-reviewed journals such as Nature Protocol, PNAS, Science Advanced, Advanced Materials, ACS Nano, Angewandte Chemie, etc. Her H index is 64, and her research has been cited over 16,300 times. Her work has also attracted funding through the BWH Stepping Strong Innovator Awards and Innovation Evergreen Award.
Micro/Nano Engineered Biomaterials for Manufacturing Biomimetic Tissues and Biomedical Applications
Tuesday, 8 November 2022 at 10:00
Add to Calendar ▼2022-11-08 10:00:002022-11-08 11:00:00Europe/LondonMicro/Nano Engineered Biomaterials for Manufacturing Biomimetic Tissues and Biomedical ApplicationsBioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com
Damage and loss to muscles are common for survivors of trauma-related injuries and disease. In cases where a patient has damaged or lost a significant amount of tissues, the body is unable to repair or regain the lost tissue. Current treatment options are limited, and many patients must undergo multiple surgeries, which are costly and bear the significant risk to the patient. However, a few significant challenges in tissue engineering still exist, such as recapitulating the in vitro, 3D hierarchical microarchitecture comprised of multiple cell types and the extracellular matrix (ECM) components of native tissues and achieving the continuous function and viability of engineered tissues after implantation. To create biomimetic tissue constructs, we developed an advanced multi-material bioprinting platform that employs self-healing supporting baths and a programmable microfluidic device, which can easily and quickly switch between different materials, biological reagents, and cells. This advanced bioprinting platform allowed us to fabricate complex geometrical structures such as centimeter-sized biomimetic uni- or bi-cellular tissue constructs. Another challenge is the survival of bioprinted 3D tissue constructs at the injured area, which is fully dependent on the oxygenation derived by its connection to the blood circulation of the host body. Incorporating functional vasculatures or oxygenating biomaterials could potentially solve this problem, as it immediately allows for the perfusion of blood, thus offering instant and ample amounts of oxygen and nutrients. We have developed oxygen-generating biomaterials containing molecules that release oxygen upon hydrolysis that allow the implant to survive their non-perfused phase and enable the continued function and maturation of living implants. The successful development of these innovative systems is expected to improve tissue regeneration significantly.
Add to Calendar ▼2022-11-07 00:00:002022-11-08 00:00:00Europe/LondonBioprinting and Bioink Innovations for 3D-Tissues 2022Bioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2022-11-08 10:00:002022-11-08 11:00:00Europe/LondonMicro/Nano Engineered Biomaterials for Manufacturing Biomimetic Tissues and Biomedical ApplicationsBioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com
