Bill Lu,
Associate Professor,
Santa Clara University
Biao Lu, MD, PhD, is an Associate Professor in Bioengineering at Santa Clara University. He has published over 60 peer-reviewed manuscripts; 4 book chapters and 43 peer-reviewed conference proceeding papers, and has 4 patents. His major discoveries in the field of nanoscale exosomes include: (1) invented exosome surface display technology using tetraspanins such as CD9, CD61, and CD81; (2) invented pseudotyping technology for genetic modification of exosomes in cultured human cells; (3) Genetic engineering strategies using human cell-derived exosomes for the treatment of inflammation and lysosomal storage diseases; and (4) currently working on exosome-based vaccination for viral infections and for the prevention and treatment of cancers.
Genetic Engineering of Nanoscale Exosomes for Targeted Drug Delivery and Therapy
Thursday, 27 July 2023 at 15:00
Add to Calendar ▼2023-07-27 15:00:002023-07-27 16:00:00Europe/LondonGenetic Engineering of Nanoscale Exosomes for Targeted Drug Delivery and TherapyExtracellular Vesicles 2023: Drug Delivery, Biologics and Therapeutics in Orlando, FloridaOrlando, FloridaSELECTBIOenquiries@selectbiosciences.com
Human cell-derived nanoscale exosomes are the fast-growing class of biologics with potential treatments of many difficult-to-manage human diseases such as cancer, hereditary and genetic defect, viral infection and inflammation, as well as cardiovascular and neurological disease. Owning to their intrinsic biocompatibility, high tissue-penetrating ability, and large capacity in delivery of various biological cargos, exosomes have overtaken the traditional small-molecular therapeutic paradigm and opened new horizons in advanced therapeutic applications. This seminal talk focuses on novel techniques for exosome surface engineering on functional moiety installation, drug loading and intracellular delivery. Furthermore, specific examples of how exosomes are engineered to display targeting moieties on their outer surface or to load therapeutic agents in living human cells are also discussed.
Add to Calendar ▼2023-07-26 00:00:002023-07-27 00:00:00Europe/LondonExtracellular Vesicles 2023: Drug Delivery, Biologics and TherapeuticsExtracellular Vesicles 2023: Drug Delivery, Biologics and Therapeutics in Orlando, FloridaOrlando, FloridaSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2023-07-27 15:00:002023-07-27 16:00:00Europe/LondonGenetic Engineering of Nanoscale Exosomes for Targeted Drug Delivery and TherapyExtracellular Vesicles 2023: Drug Delivery, Biologics and Therapeutics in Orlando, FloridaOrlando, FloridaSELECTBIOenquiries@selectbiosciences.com
