Roy van der Meel,
Assistant Professor, Department of Biomedical Engineering, ,
Eindhoven University of Technology
Roy van der Meel is a biomedical engineer specialized in nanomedicine and RNA therapeutics. After obtaining a PhD from Utrecht University, he worked as a postdoc in Pieter Cullis’ lab at the University of British Columbia. Since 2019, Roy is appointed Assistant Professor of Precision Medicine at Eindhoven University of Technology. His current research is focused on establishing platform nanotechnology for delivering RNA therapeutics to regulate the immune system.
Gene Silencing in HSPCs with an Apolipoprotein A1-based Nanodelivery Platform
Tuesday, 14 November 2023 at 14:00
Add to Calendar ▼2023-11-14 14:00:002023-11-14 15:00:00Europe/LondonGene Silencing in HSPCs with an Apolipoprotein A1-based Nanodelivery PlatformExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Nucleic acid therapeutics are revolutionizing healthcare via gene inhibition, addition, replacement or editing. However, nucleic acid-based drugs require chemical modifications and sophisticated nanotechnology to prevent their degradation, reduce immunostimulatory effects, and ensure intracellular delivery. Lipid nanoparticle (LNP) technology is the current gold standard platform that enabled the clinical translation of the first siRNA drug Onpattro and the COVID-19 mRNA vaccines. Nevertheless, current LNP systems are mostly suited for vaccine purposes following local administration or hepatic delivery following intravenous administration. To unleash RNA’s full therapeutic potential, we introduce modular nanoplatform technology for systemic nucleic acid delivery to immune cells in hematopoietic organs using apolipoproteins.
Add to Calendar ▼2023-11-13 00:00:002023-11-14 00:00:00Europe/LondonExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023Extracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2023-11-14 14:00:002023-11-14 15:00:00Europe/LondonGene Silencing in HSPCs with an Apolipoprotein A1-based Nanodelivery PlatformExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
