Aalim Weljie,
Research Assistant Professor,
University of Calgary
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Metabolomics as a Platform for High-Throughput Biomarker Discovery in Cancer
Tuesday, 8 November 2011 at 14:15
Add to Calendar ▼2011-11-08 14:15:002011-11-08 15:15:00Europe/LondonMetabolomics as a Platform for High-Throughput Biomarker Discovery in Cancer Advances in Metabolic Profiling in Dublin, IrelandDublin, IrelandSELECTBIOenquiries@selectbiosciences.com
Data will be presented from cohorts of pancreatic, colon and brain tumors patients. Analysis of these biomarkers is performed using a pattern-driven approach, and as such analytical techniques which are both quantitative and high-throughput are favoured. The outcome is information with respect to a ‘biopattern’ of disease without the requirement for comprehensively attempting to characterize the entire metabolome. Furthermore, the resulting multivariate data is characterized by concerted changes in multiple markers, in contrast with traditional biomarker-driven approaches that rely on single markers. Finally, several challenges in the evolution of the field will be discussed, including interpreting coherent biological meaning from a combination of both NMR and MS data, and reliable assessment of candidate markers using multivariate statistics.
Add to Calendar ▼2011-11-08 00:00:002011-11-09 00:00:00Europe/LondonAdvances in Metabolic ProfilingAdvances in Metabolic Profiling in Dublin, IrelandDublin, IrelandSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2011-11-08 14:15:002011-11-08 15:15:00Europe/LondonMetabolomics as a Platform for High-Throughput Biomarker Discovery in Cancer Advances in Metabolic Profiling in Dublin, IrelandDublin, IrelandSELECTBIOenquiries@selectbiosciences.com
