| Conferences \ European Lab Automation \ Screening Europe - HCS and Assays \ Agenda \ Remko de Pril |
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High Content Screen for Inhibitors of Cell Migration in Cancer Metastasis Using Adenoviral Knock-DownThursday, 30 June 2011 at 16:00  Add to Calendar ▼2011-06-30 16:00:002011-06-30 17:00:00Europe/LondonHigh Content Screen for Inhibitors of Cell Migration in Cancer Metastasis Using Adenoviral Knock-DownSELECTBIOenquiries@selectbiosciences.comEnhanced cell migration is a hallmark of metastatic cancer cells. The propensity of cancer cells to close an open wound in a cell monolayer is thought to predict this ability. Using our adenoviral shRNA knock-down library we have established a high-throughput wound healing assay to identify novel genes involved in cell migration. We demonstrated that two knock-down constructs targeting a known player in motility, CXCR4, inhibit wound healing, thereby validating our approach. |
Add to Calendar ▼2011-06-30 00:00:002011-07-01 00:00:00Europe/LondonScreening Europe - HCS and AssaysSELECTBIOenquiries@selectbiosciences.com
