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SELECTBIO Conferences Fragment Based Lead Discovery

Gregg Siegal's Biography

Gregg Siegal, Professor, Leiden University

Dr. Siegal obtained his Ph.D. on studies of eukaryotic DNA replication at the University of Rochester in the USA. Pursuing an interest in structural biology he moved to the laboratory of Professor Kurt Wüthrich at the ETH in Zürich, Switzerland. His work in the Wüthrich group focused on heteronuclear NMR studies of protein structure and folding. Subsequently he joined the group of Professor Paul Driscoll at the Ludwig Institute of Cancer Research in London, UK where he studied protein structure and small molecule interactions, again using NMR. He moved to Leiden University in 1997 where he received a Dutch Royal Society Fellowship to form his own research group. His current research interests focus on development of drug discovery technologies and their implementation in the drug discovery process. In 2004 he spun out the company ZoBio to commercialize the TINS ligand screening technology developed in his group and presently serves as the Chief Scientific Officer in addition to his position within the University.

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Filling the Hole in Your Crystal(ography) with NMR

Tuesday, 19 March 2013 at 14:45

Add to Calendar ▼2013-03-19 14:45:002013-03-19 15:45:00Europe/LondonFilling the Hole in Your Crystal(ography) with

NMR is frequently used to discover fragment hits. However, NMR can also provide timely structural information on hits weakly bound to the target.

Add to Calendar ▼2013-03-19 00:00:002013-03-20 00:00:00Europe/LondonFragment Based Lead Discovery