In 1995 Neal began his career at Rhone-Poulenc Agriculture in the UK before switching fields and joining Process Chemistry at Pfizer Sandwich, becoming the first member of the high-throughput reaction optimization group. Over the next decade the application of technology to process chemistry become increasingly valuable and Neal eventually headed up a group of five scientists, before, in 2007, he switched divisions within Pfizer and moved to Discovery Chemistry in San Diego. Neal currently applies miniaturized high-throughput screening technologies, including flow technology, to solving chemical problems in the discovery portfolio.
Sub-Micromolar Reaction Screening in Flow
Tuesday, 6 February 2018 at 15:45
Add to Calendar ▼2018-02-06 15:45:002018-02-06 16:45:00Europe/LondonSub-Micromolar Reaction Screening in FlowFlow Chemistry Europe 2018 in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
A novel segmented flow technology is presented that enables sub-µmol
scale reaction screening. This step change in scale, compared with
typical batch methods, enables the potential to examine over 1500
combinations (solvent, base, catalyst, and temperature) automatically in
24 hours using just 15mg of substrate. The presentation will
demonstrate the technology through a model Suzuki coupling in which over
5000 combinations were completed in 4 days to arrive at a scalable
process suitable for scale up, or scale-out.
Add to Calendar ▼2018-02-06 00:00:002018-02-07 00:00:00Europe/LondonFlow Chemistry Europe 2018Flow Chemistry Europe 2018 in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2018-02-06 15:45:002018-02-06 16:45:00Europe/LondonSub-Micromolar Reaction Screening in FlowFlow Chemistry Europe 2018 in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
